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Table 1 Subject’s characteristics in Euthyroid group and Euthyroid women with TPOAb positivity group

From: Relationship between anti-thyroid peroxidase antibody positivity and pregnancy-related and fetal outcomes in Euthyroid women: a single-center cohort study

 

Euthyroid group (n = 837)

Euthyroid women with TPOAb positivity group (n = 101)

Statistics

P

Maternal age (years)

30 (28,34)

31 (29,34)

−1.660

0.097

Age ≥ 35 years (%)

157 (18.8%)

21 (20.8%)

0.243

0.622

BMI (kg/m2)

21.48 (19.81,23.43)

21.35 (20.07,23.19)

−0.149

0.881

BMI ≥ 24 kg/m2 (%)

174 (20.8%)

19 (18.8%)

0.215

0.643

Parity (%)

 primipara

519 (62.0%)

60 (59.4%)

0.258

0.611

 multipara

318 (38.0%)

41 (40.6%)

  

History of spontaneous abortion (%)

114 (13.6%)

11 (10.9%)

0.581

0.446

HbA1c (%)

5.1 (4.9,5.3)

5.1 (5.0,5.3)

−1.174

0.240

GS (mmol/L)

4.88 (4.65,5.14)

4.85 (4.65,5.15)

−0.175

0.861

TSH (uIU/ml)

1.31 (0.826,1.80)

1.51 (1.14,2.08)

−3.793

0.000*

FT4 (pmol/L)

17.20 (15.80,18.50)

16.9 (15.80,18.80)

−0.318

0.751

LDL (mmol/L)

2.02 (1.69,2.37)

1.98 (1.77,2.28)

−0.426

0.670

UA (μmol/L)

209 (181,236)

215 (189,239)

−0.841

0.401

Hcy (μmol/L)

6.40 (5.70,7.20)

6.1 (5.70,7.38)

−0.224

0.823

Ferritin (ng/ml)

53.1 (33.03,80.95)

48.75 (29.95,69.30)

−1.426

0.154

  1. *P < 0.05
  2. Statistics: Maternal age, BMI, FT4, TSH, GS, HbA1c, LDL, UA, Hcy and Ferritin for Mann-Whitney U test; Age<35 years, BMI<24 kg/m2, parity, and history of spontaneous abortion for chi-square test or Fisher test
  3. Continuous data are expressed as median (interquartile range). Categorical data are expressed as numbers (percentages) of cases
  4. BMI body-mass index, TSH thyroid-stimulating hormone, FT4 free thyroxine, HbA1c glycated hemoglobin, GS blood glucose, LDL low density lipoprotein cholesterol, UA uric acid, Hcy homocysteine