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Table 3 Free β-hCG, PAPP-A and NTT in the first trimester screening analysis

From: The effect of maternal alcohol and drug abuse on first trimester screening analytes: a retrospective cohort study

 

Controls (n=217)

Abusers (n=71)

Smokers (n=88)

SGA mothers (n=168)

Median

Mean

SD

Median

Mean

SD

MD (95% CI)

P

Median

Mean

SD

MD (95% CI)

P

Median

Mean

SD

MD (95% CI)

P

β-hCG MoM

1.02

1.21

0.72

1.24

1.5

0.88

-0.29 (-0.50, -0.09)

0.013

1.18

1.45

1.06

-0.25 (-0.49, -0.01)

0.048

1.02

1.24

0.82

-0.03 (-0.18, 0.12)

0.700

PAPP-A MoM

1.04

1.20

0.76

0.90

1.14

0.78

0.06 (-0.15, 0.27)

0.197

0.83

0.90

0.47

0.31 (0.16, 0.45)

<0.001

0.90

1.08

0.64

0.12 (-0.02, 0.26)

0.043

NTT MoM

0.90

0.92

0.27

0.89

0.92

0.24

0.01 (-0.06, 0.08)

0.882

0.90

1.02

0.59

-0.09 (-0.19, 0.01)

0.145

0.91

0.98

0.38

-0.06 (-0.12, 0.01)

0.078

  1. Independent samples t-test was used for the free β-hCG, PAPP-A and fetal NTT MoM values in comparison with the Controls. MD Mean difference, CI 95% confidence interval of the difference, MoM Multiples of medians