Skip to main content

Table 2 First (11–13 weeks), second (19–22 weeks) and third (27–30 weeks) trimester evaluation

From: “Screening for small-for-gestational age neonates at early third trimester in a high-risk population for preeclampsia”

 

Normal birthweight (n = 328)

SGA (n = 50)

P

First trimester evaluation

 - Mean uterine artery PI (MoM)

1.2 ± 0.3

1.4 ± 0.3

< 0.001*

 - MAP (mm Hg)

85.8 ± 7.9

82.0 ± 7.1

0.002*

 - PAPP-A (MoM)

1 ± 0.5

0.8 ± 0.4

0.039*

 - PlGF (MoM)

0.3 ± 0.2

0.2 ± 0.2

0.002*

Second trimester evaluation

 - Mean uterine artery PI (MoM)

1.2 ± 0.6

1.6 ±0.5

< 0.001*

Third trimester evaluation

 - EFW (g)

1399.3 ± 173.2

1244.5 ± 149.0

< 0.001*

 - EFW (z-scores)

0.1 ± 1.0

-0.7 ± 0.9

< 0.001*

 - Mean uterine artery PI (MoM)

1.2 ± 0.4

1.4 ± 0.5

< 0.001*

 - MAP (mmHg)

81.9 ± 10.3

80.5 ± 9.9

0.372

 - PlGF (pg/mL)

530.9 ± 423.1

328.4 ± 287.8

< 0.001*

 - PlGF (MoM)

1.13 ± 0.9

0.70 ± 0.62

< 0.001*

 - sFlt-1 (pg/mL)

1385.5 ± 1118.7

1692.5 ± 1206.7

0.037*

 - sFlt-1 (MoM)

0.9 ± 0.7

1.1 ± 0.8

0.037*

 - sFlt-1/PlGF

6.2 ± 17.1

14.7 ± 21.7

< 0.001*

 - sFlt-1/PlGF (MoM)

1.8 ± 5.2

4.5 ± 6.8

< 0.001*

  1. Quantitative variables were expressed as mean ± SD
  2. (*p < 0.05)
  3. SGA Small-for-gestational age neonates, PI Pulsatility index, MoM Multiples of the median, MAP Mean arterial pressure, PAPP-A Pregnancy-associated plasma protein A, PlGF Placental growth factor, EFW Estimated fetal weight, sFlt-1 Soluble FMS-Like Tyrosine Kinase-1