Skip to main content

Table 4 Frequency distribution of estimated parasite densities of P .falciparum infections detected by each diagnostic test

From: Evaluation of highly sensitive diagnostic tools for the detection of P. falciparum in pregnant women attending antenatal care visits in Colombia

Diagnostic test n No. of infections detected by parasite density category (% of qRT-PCR-positive) a
<  1 p/μL 1–10 p/μL 10–100 p/μL > 100 p/μL
(n = 12) (n = 3) (n = 9) (n = 14)
Microscopy 22 0 (0) 0 (0) 8 (88.9) 14 (100)
cRDT 20 0 (0) 0 (0) 6 (66.7) 14 (100)
hsRDT 24 1 (8.3) 0 (0) 9 (100) 14(100)
LAMP 34 9 (75.0) 2 (66.7) 9 (100) 14 (100)
nPCR 29 5 (41.7) 1 (33.3) 9 (100) 14 (100)
  1. aRefers to P. falciparum mono-infections (i.e., mixed infection not included. p/μL: estimated parasites per microliter, qRT-PCR Quantitative Reverse Transcription polymerase chain reaction, cRDT conventional rapid diagnostic test, hsRDT highly sensitive rapid diagnostic test, nPCR nested polymerase chain reaction, LAMP loop-mediated isothermal amplification