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Table 2 Relationship between Ca intake and hypertensive disorder of pregnancy

From: Association between pre-pregnancy calcium intake and hypertensive disorders during the first pregnancy: the Japan environment and children’s study

 

Threshold of Ca intake

500 mg/day

550 mg/day

650 mg/day

700 mg/day

1000 mg/day

1500 mg/day

2000 mg/day

Participants with intake > threshold, %

38.9%

32.1%

21.6%

18.0%

7.9%

3.3%

2.0%

HDP

 Occurrence, %

3.3%

3.3%

3.3%

3.3%

3.2%

3.2%

3.2%

 OR (95% CI)

0.96 (0.85–1.09)

0.98 (0.86–1.11)

0.95 (0.82–1.10)

0.90 (0.77–1.06)

1.04 (0.84–1.30)

1.25 (0.92–1.69)

1.25 (0.84–1.84)

 aOR (95% CI)

0.96 (0.85–1.09)

0.98 (0.86–1.11)

0.95 (0.82–1.10)

0.89 (0.76–1.05)

1.04 (0.83–1.15)

1.20 (0.88–1.63)

1.22 (0.83–1.81)

Eo-HDP

 Occurrence, %

0.6%

0.6%

0.6%

0.6%

0.6%

0.6%

0.6%

 OR (95% CI)

0.95 (0.71–1.27)

1.02 (0.75–1.38)

0.96 (0.68–1.36)

0.91 (0.63–1.34)

1.22 (0.75–1.99)

1.27 (0.63–2.59)

1.05 (0.39–2.84)

 aOR (95% CI)

0.91 (0.68–1.23)

0.99 (0.73–1.34)

0.93 (0.65–1.32)

0.88 (0.60–1.29)

1.19 (0.73–1.95)

1.19 (0.58–2.43)

1.02 (0.38–2.77)

Lo-HDP

 Occurrence, %

2.4%

2.4%

2.4%

2.4%

2.4%

2.3%

2.4%

 OR (95% CI)

0.97 (0.84–1.12)

0.97 (0.84–1.13)

0.94 (0.79–1.12)

0.88 (0.73–1.06)

1.04 (0.80–1.34)

1.26 (0.88–1.79)

1.20 (0.76–1.91)

 aOR (95% CI)

0.97 (0.84–1.13)

0.97 (0.84–1.13)

0.94 (0.79–1.12)

0.88 (0.73–1.06)

1.03 (0.80–1.34)

1.22 (0.86–1.75)

1.19 (0.75–1.89)

  1. Ca Calcium, HDP Hypertensive disorder of pregnancy, Eo Early onset, Lo Late onset, OR Odds ratio, aOR Adjusted odds ratio, CI Confidence interval, Ref Reference
  2. aOR was calculated by logistic regression analysis, using reference cut value (< threshold or more than threshold), maternal age (< 35 years), parity, method of conception, pre-pregnancy BMI, maternal smoking status, maternal education, and household income