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Table 2 Relationship between Ca intake and hypertensive disorder of pregnancy

From: Association between pre-pregnancy calcium intake and hypertensive disorders during the first pregnancy: the Japan environment and children’s study

  Threshold of Ca intake
500 mg/day 550 mg/day 650 mg/day 700 mg/day 1000 mg/day 1500 mg/day 2000 mg/day
Participants with intake > threshold, % 38.9% 32.1% 21.6% 18.0% 7.9% 3.3% 2.0%
HDP
 Occurrence, % 3.3% 3.3% 3.3% 3.3% 3.2% 3.2% 3.2%
 OR (95% CI) 0.96 (0.85–1.09) 0.98 (0.86–1.11) 0.95 (0.82–1.10) 0.90 (0.77–1.06) 1.04 (0.84–1.30) 1.25 (0.92–1.69) 1.25 (0.84–1.84)
 aOR (95% CI) 0.96 (0.85–1.09) 0.98 (0.86–1.11) 0.95 (0.82–1.10) 0.89 (0.76–1.05) 1.04 (0.83–1.15) 1.20 (0.88–1.63) 1.22 (0.83–1.81)
Eo-HDP
 Occurrence, % 0.6% 0.6% 0.6% 0.6% 0.6% 0.6% 0.6%
 OR (95% CI) 0.95 (0.71–1.27) 1.02 (0.75–1.38) 0.96 (0.68–1.36) 0.91 (0.63–1.34) 1.22 (0.75–1.99) 1.27 (0.63–2.59) 1.05 (0.39–2.84)
 aOR (95% CI) 0.91 (0.68–1.23) 0.99 (0.73–1.34) 0.93 (0.65–1.32) 0.88 (0.60–1.29) 1.19 (0.73–1.95) 1.19 (0.58–2.43) 1.02 (0.38–2.77)
Lo-HDP
 Occurrence, % 2.4% 2.4% 2.4% 2.4% 2.4% 2.3% 2.4%
 OR (95% CI) 0.97 (0.84–1.12) 0.97 (0.84–1.13) 0.94 (0.79–1.12) 0.88 (0.73–1.06) 1.04 (0.80–1.34) 1.26 (0.88–1.79) 1.20 (0.76–1.91)
 aOR (95% CI) 0.97 (0.84–1.13) 0.97 (0.84–1.13) 0.94 (0.79–1.12) 0.88 (0.73–1.06) 1.03 (0.80–1.34) 1.22 (0.86–1.75) 1.19 (0.75–1.89)
  1. Ca Calcium, HDP Hypertensive disorder of pregnancy, Eo Early onset, Lo Late onset, OR Odds ratio, aOR Adjusted odds ratio, CI Confidence interval, Ref Reference
  2. aOR was calculated by logistic regression analysis, using reference cut value (< threshold or more than threshold), maternal age (< 35 years), parity, method of conception, pre-pregnancy BMI, maternal smoking status, maternal education, and household income