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Table 1 Clinical characteristics and baseline demographic parameters of the cohort (n = 56)

From: Cerebral hemodynamic response to short-term maternal hyperoxygenation in fetuses with borderline small left hearts

  Foetus younger than 28 weeks GA (group I) P Foetus older than 28 weeks GA (group II) P
Normal (n = 12) Borderline small left heart (n = 12) Normal (n = 16) Borderline small left heart (n = 16)
Maternal age (years) 29 ± 6 28 ± 6 0.75 30 ± 5 29 ± 6 0.53
Nulliparous, n (%) 6 8 0.68 8 7 1.0
AR pregnancy 2 5 0.37 1 4 0.3
GA at diagnosis (weeks) 25.8 ± 1.2 25.8 ± 1.2 1.00 32.5 ± 2.5 32.5 ± 2.5 1.00
EFW at diagnosis (g) 832 ± 121 868 ± 152 0.53 1993 ± 525 2000 ± 533 0.97
GA at birth (weeks) 39.0 ± 1.0 38.2 ± 0.8 0.06 40.2 ± 0.8 39.6 ± 0.8 0.05
Weight at birth (g) 3448 ± 259 3033 ± 248 0.001 3575 ± 159 3422 ± 259 0.05
BPD (mm) 64.9 ± 0.5 64.8 ± 0.4 0.95 83.5 ± 0.6 81.4 ± 0.5 0.28
HC (mm) 238.0 ± 1.4 236.5 ± 1.5 0.80 293.4 ± 1.7 283.1 ± 1.5 0.08
FHR (bpm) 152 ± 7 154 ± 8 0.78 154 ± 6 154 ± 7 0.96
MCA-PI 1.62 ± 0.19 1.61 ± 0.19 0.92 1.79 ± 0.22 1.44 ± 0.27 < 0.001
UA-PI 1.19 ± 0.22 1.14 ± 0.13 0.47 0.96 ± 0.22 1.11 ± 0.19 0.05
MV Z-score 0.00 ± 0.19 −2.24 ± 0.27 < 0.001 − 0.02 ± 0.40 − 2.23 ± 0.28 < 0.001
TV Z-score −0.05 ± 0.24 0.15 ± 0.29 0.07 0.03 ± 0.25 0.12 ± 0.36 0.43
AV Z-score −0.06 ± 0.39 −2.33 ± 0.33 < 0.001 −0.02 ± 0.32 −2.28 ± 0.24 < 0.001
PV Z-score −0.06 ± 0.28 0.06 ± 0.29 0.34 −0.06 ± 0.38 0.08 ± 0.49 0.56
VI 1.72 ± 0.29 1.70 ± 0.26 0.81 2.00 ± 0.34 3.19 ± 0.87 < 0.001
FI 33.00 ± 4.29 33.28 ± 3.85 0.56 37.52 ± 2.86 56.91 ± 9.19 < 0.001
VFI 0.60 ± 0.22 0.62 ± 0.18 0.82 0.84 ± 0.16 1.30 ± 0.33 < 0.001
CCOi (mL/min/kg) 427.52 ± 73.73 436.68 ± 66.33 0.75 501.42 ± 79.56 462.88 ± 74.42 0.17
  1. AR assisted reproduction, GA gestational age, EFW estimated foetal weight, FHR foetal heart rate, PI pulsatility index, MCA middle cerebral artery, UA umbilical artery, MV mitral valve, TV tricuspid valve, AV aortic valve, PV pulmonary artery valve, VI vascular index, FI flow index, VFI vascular/flow index, CCOi combined cardiac output index