Table 2 Logistic regression to identify interactions between maternal prepregnancy BMI and risk of CHDs in offspring
Subgroup | CHDs n (%) | No CHDs n (%) | cOR(95%CI) c | aOR (95%CI) d | mOR(95%CI) e |
|---|---|---|---|---|---|
All subjects | |||||
 BMI < 18.5 | 333 (27.61) | 274 (24.64) | 1.34 (1.06,1.70) | 1.40 (1.06,1.83) | 1.53 (1.13,2.08) |
 18.5 ≤ BMI < 21.25 | 540 (44.78) | 484 (44.78) | 1.23 (1.00,1.53) | 1.26 (0.99,1.61)†| 1.44 (1.10,1.89) |
 21.25 ≤ BMI < 24.00 | 236 (19.57) | 261 (23.47) | Reference | Reference | Reference |
 BMI ≥ 24.00 | 97 (8.04) | 93 (8.36) | 1.15 (0.83,1.61) | 1.19 (0.81,1.75) | 1.29 (0.84,1.97) |
Single CHD a | |||||
 BMI < 18.5 | 191 (26.71) | 274 (24.64) | 1.25 (0.95,1.65) | 1.39 (1.01,1.92) | 1.61 (1.12,2.31) |
 18.5 ≤ BMI < 21.25 | 326 (45.59) | 484 (44.78) | 1.21 (0.95,1.55) | 1.36 (1.02,1.81) | 1.63 (1.18,2.26) |
 21.25 ≤ BMI < 24.00 | 145 (20.28) | 261 (23.47) | Reference | Reference | Reference |
 BMI ≥ 24.00 | 53 (7.41) | 93 (8.36) | 1.03 (0.69,1.52) | 1.08 (0.68,1.71) | 1.19 (0.71,1.98) |
Multiple CHDs b | |||||
 BMI < 18.5 | 142 (28.92) | 274 (24.64) | 1.49 (1.09,2.03) | 1.41 (0.98,2.01)†| 1.46 (0.98,2.16)†|
 18.5 ≤ BMI < 21.25 | 214 (43.58) | 484 (44.78) | 1.27 (0.95,1.69) | 1.11 (0.80,1.55) | 1.17 (0.81,1.67) |
 21.25 ≤ BMI < 24.00 | 91 (18.53) | 261 (23.47) | Reference | Reference | Reference |
 BMI ≥ 24.00 | 44 (8.96) | 93 (8.36) | 1.36 (0.88,2.09) | 1.34 (0.81,2.20) | 1.34 (0.78,2.30) |