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Table 5 Diagnostic values of discordances of fetal growth parameters in the early third-trimester for growth discordancea

From: Predictive value of prenatal ultrasound parameters for dichorionic growth discordant twins

Parameter Early third-trimester
AUC P 95% CI Youden index Cut-off (%) Sensitivity (%) Specificity (%) PPV (%) NPV (%) +LR
BPD 0.688 0.004 0.62–0.75 0.34 4.60 71.43 62.50 65.57 68.63 1.90
HC 0.672 0.086 0.56–0.77 0.39 7.07 42.86 95.83 91.13 62.65 10.28
AC 0.740 < 0.001 0.67–0.80 0.40 8.02 57.14 83.43 77.52 66.06 3.45
FL 0.780 < 0.001 0.72–0.83 0.46 5.26 66.67 79.89 76.83 70.56 3.31
EFW 0.822 < 0.001 0.76–0.87 0.58 20.36 66.67 91.30 88.46 73.26 7.66
  1. aBPD biparietal diameter; HC head circumference; AC abdominal circumference; FL femur length; EFW estimated fetal weight; AUC area under the curve; CI confidence interval; PPV positive predictive value; NPV negative predictive value; +LR positive likelihood ratio