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Table 2 The estimated diagnostic accuracy parameters for composite test from Bayesian latent class model adjusting for maternal age and BMI

From: Diagnostic accuracy of maternal serum multiple marker screening for early detection of gestational diabetes mellitus in the absence of a gold standard test

BiomarkerParameterMeanMedianSDMC error95% CrI
uE3 and β-hCG
 cSensitivity0.680.660.140.010.64–0.75
cSpecificity0.660.650.220.020.61–0.77
cAUC0.700.700.110.010.62–0.78
uE3 and AFP
 cSensitivity0.760.780.360.010.70–0.82
cSpecificity0.720.710.150.010.66–0.78
cAUC0.870.870.140.020.81–0.91
AFP and β-hCG
 cSensitivity0.720.740.420.050.68–0.81
cSpecificity0.750.750.230.010.68–0.84
cAUC0.790.780.210.020.71–0.87
uE3 and β-hCG and AFP
 cSensitivity0.940.950.060.0010.91–0.99
cSpecificity0.860.860.150.020.80–0.92
cAUC0.920.910.110.010.87–0.98
  1. uE3 unconjugated estriol, β-hCG beta-human chorionic gonadotropin, AFP alfa-fetoprotein, SD standard deviation, MC monte carlo, CrI credible interval, cSensitivity combined Sensitivity, cSpecificity combined Specificity, cAUC combined area under receiver operating characteristic curve