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Table 2 Outcomes following outpatient vs. inpatient induction: main analysis

From: Inpatient versus outpatient induction of labour: a systematic review and meta-analysis

Outcome

Studies

Outpatient events

Inpatient events

Estimate (95% CI)

I2

Maternal morbidity and patient-reported outcomes

 Chorioamnionitis during labour

6

74/839 (8.82%)

68/834 (8.15%)

RR 1.09 (0.80, 1.48)

0

 Maternal hyperstimulation

5

12/858 (1.40%)

17/865 (1.97%)

RR 0.72 (0.21, 2.41)

35.80

 Postpartum haemorrhage > 500 mL (vaginal births)

4

132/709 (18.62%)

123/715 (17.20%)

RR 1.10 (0.89, 1.37)

0

 Mean hospital anxiety-depression score

2

NA

NA

MD −0.045 points (− 0.32, 0.23)

5.97

Fetal and neonatal outcomes

 Neonatal Intensive Care Unit Admissions

8

76/1269 (5.55%)

82/1244 (6.59%)

RR 0.93 (0.69, 1.26)

0

 5-min Apgar score < 7

5

22/994 (2.21%)

15/979 (1.53%)

RR 1.39 (0.73, 2.65)

0

 Meconium stained amniotic fluid

4

129/724 (17.82%)

123/728 (16.90%)

RR 1.06 (0.85, 1.32)

0

 Uterine hyperstimulation

4

12/643 (1.87%)

10/632 (1.58%)

RR 1.12 (0.47, 2.69)

0

 Perinatal mortality

3

1/691 (0.14%)a

0/714 (0%)

RR 1.65 (0.20, 13.32)

0

 Febrile morbidity or Antibiotic requirement

3

29/518 (5.60%)

31/499 (6.21%)

RR 0.82 (0.29, 2.30)

25.02

Suspicious fetal heart tracing

2

61/199 (30.65%)

43/201 (21.39%)

RR 1.43 (1.10, 1.86)

0

 Hypoxic ischemic Encephalopathy

2

3/626 (0.48%)

3/649 (0.46%)

RR 1.02 (0.23, 4.48)

0

 Respiratory problems

2

17/444 (3.83%)

18/431 (4.18%)

RR 0.92 (0.48, 1.75)

0

Labour outcomes

 Caesarean delivery

9

280/1319 (21.23%)

279/1295 (21.54%)

RR 0.96 (0.77, 1.19)

40.16

 Spontaneous vaginal birth

8

495/1258 (39.35%)

484/1245 (38.88)

RR 1.02 (0.88, 1.19)

67.58

 Assisted vaginal birth

8

231/1258 (18.36%)

225/1245 (18.07%)

RR 1.03 (0.85, 1.25)

12.93

 Cervical priming time

4

NA

NA

MD 25.87 min (− 142.72, + 194.45)

82.06

 Participants entering labour or delivery within 24 h of induction

4

221/643 (34.37%)

230/632 (36.39%)

RR 0.93 (0.71, 1.22)

56.59

 Mean length of active labour (vaginal births)

2

NA

NA

MD 12.42 h (−29.51, 54.35)

0

Resource-related outcomes

 Need for oxytocin infusion

6

615/1128 (54.52%)

453/1116 (40.59%)

RR 1.31 (0.95, 1.82)

93.12

 Epidural use

5

605/1078 (56.12%)

395/1078 (36.66%)

RR 1.32 (0.84, 2.07)

96.01

 Total hospital admission time until delivery

5

NA

NA

MD − 171.50 min (− 475.98, + 132.97)

90.93

 Mean duration oxytocin infusion

5

NA

NA

MD 43.87 min (−64.76, + 150.50)

82.58

Mean length of hospital stay

4

NA

NA

MD − 282.48 min (−404.73, −160.23)

10.99

 Total induction-to-delivery time

4

NA

NA

MD −107.98 min (− 332.73, + 116.78)

67.06

 Mean hospital cost per womanb

2

NA

NA

MD $144.83 (− 819.44, + 1109.10)

37.52

  1. Bold type indicates statistically significant difference between arms
  2. NA not applicable, RR risk ratio, MD mean difference, CI confidence intervals
  3. aThe case of perinatal mortality occurred for a woman who was scheduled for an outpatient induction, but did not require ripening as she entered laboured spontaneously
  4. bCosts are expressed in 2012 Australian dollars