From: Inpatient versus outpatient induction of labour: a systematic review and meta-analysis
Study (Country) | Study Population a | Outpatient arm | Inpatient arm | Primary outcome |
---|---|---|---|---|
Beckmann, 2019 [10] (Australia) | ≥37 + 0 weeks’ gestation, Bishop score < 7, residing < 60 min from the hospital | Priming with balloon catheter (n = 215) | Priming with prostaglandin 2 mg gel or 10 mg controlled-release tape (n = 233) | Composite measure of neonatal outcomes comprising of one or more of: admission to a neonatal special or intensive care nursery, need for intubation, and/or external cardiac compressions at birth, neonatal academia at birth, hypoxic ischaemic encephalopathy, neonatal seizure, neonatal infection, persistent pulmonary hypertension of the newborn, stillbirth or neonatal death |
Kuper, 2018 [11] (USA) | Parous women ≥39 weeks’ gestation, cervical dilation ≤3 cm, or if 2-3 cm dilated less than 80% effacement, reassuring fetal heart rate monitoring | Priming with balloon catheter, with oxytocin initiated upon readmission (n = 65) | Priming with balloon catheter and concomitant oxytocin infusion (n = 64) | Duration of time from labour ward admission until delivery |
Policiano, 2016 [12] (Portugal) | ≥41 weeks’ gestation or with a medical indication for labour induction), Bishop score < 6 | Priming with balloon catheter (n = 65) | Priming with balloon catheter (n = 65) | Change of Bishop score between application and removal of balloon catheter |
Wilkinson 2015, [18] COPRA Trial (Australia) | 37–42 weeks’ gestation, Bishop score < 7 | Priming with balloon catheter (n = 33) | Priming with balloon catheter (n = 15) | Oxytocin use |
Women ≥18 years old, ≥37 weeks’ gestation, Bishop score < 7 and cervical dilation < 2 cm, no regular uterine contractions. | Priming with balloon catheter (n = 50) | Priming with vaginal prostaglandin E2 gel [2 mg for nulliparous and 1 mg for parous women] (n = 51) | Vaginal birth within 12 h of admission, inpatient hours between randomization and birth | |
Wilkinson 2014 [15], Turnbull 2013 [16] & Adelson 2013 [17], OPRA Trial (Australia) | Women ≥18 years of age, 37–42 weeks’ gestation, living within 40 min of hospital with transport and having a telephone. | Priming with prostaglandin E2 gel [2 mg for nulliparous and 1 mg for parous women] (n = 411) | Priming with prostaglandin E2 gel [2 mg for nulliparous and 1 mg for parous women] (n = 416) | Oxytocin use |
Rijnders 2011 [21] (Netherlands) | Women ≥18 years of age, 41 + 5–42 weeks’ gestation, no neonatal infections in previous pregnancies, and negative GBS status. | Amniotomy (at home) followed by 12 h of expectant management (n = 270) | Referral to an obstetrician for monitoring and induction of labour according to local guidelines. (n = 251) | Spontaneous birth without intervention. |
Biem 2002 [20](Canada) | ≥ 37 weeks’ gestation, a reactive non-stress test, Bishop score ≤ 6, and reliable means of transportation to the hospital. | Priming with prostaglandin E2 10mg insert, and admitted 24 h after insertion (n = 150) | Priming with prostaglandin E2 10mg insert (n = 150) | Proportion in labour or delivered by 24 h, and maternal satisfaction. |
Sciscione 2001 [19] (USA) | ≥ 37 weeks’ gestation, Bishop score ≤ 5, access to a telephone, and living within 30 min from the hospital with reliable means of transportation. | Priming with balloon catheter followed by oxytocin infusion the next morning of cervical ripening until extrusion of catheter (n = 61) | Priming with balloon catheter, then oxytocin infusion was started once the catheter was extruded (n = 50) | Change in Bishop score from the initial assessment until reassessment the following morning for outpatients, or when the Foley was extruded for inpatients. |