Meta-analyses | Studies | References | Patients n | Shape of association | Risk ratio | 95% CI | I2 |
---|---|---|---|---|---|---|---|
NICU admission all | 14 | 898,272 | Linear dose-responsea | 0.63 | 0.56–0.71 | 95.4 | |
Neonatal death | 4 | 533,880 | U-Shapeb | < 39: 0.59 ≥39: 2.09 | 0.43–0.83 1.18–3.70 | 77.5 | |
Respiratory morbidity | 9 | 57,693 | Linear dose-responsea | 0.64 | 0.51–0.79 | 95.2 | |
Hospitalization ≥5 days | 5 | 59,331 | U-Shapeb | < 39 0.52 ≥39 2.00 | 0.36–0.75 1.40–2.86 | 96.2 | |
Sepsis | 4 | 42,381 | U-Shapeb | < 39 0.55 ≥39 3.57 | 0.44–0.67 1.87–6.78 | 21.8 | |
Hypoglycemia | 6 | 46,367 | Linear dose-responsea | 0.84 | 0.79–0.91 | 0.0 | |
Apgar Score < 7 | 5 | 805,274 | Linear dose-responsea | 0.90 | 0.69–1.17 | 65.7 | |
Jaundice | 5 | 32,109 | Linear dose-responsea | 0.71 | 0.66–0.77 | 53.7 | |
Respiratory distress syndrome | 5 | 43,888 | Linear dose-responsea | 0.60 | 0.54–0.67 | 45.0 | |
Transient tachypnea of the newborn | 5 | 40,766 | Linear dose-responsea | 0.68 | 0.54–0.86 | 84.1 | |
Pneumothorax | 4 | 25,121 | Binary (37 + 38 WG vs. ≥39 WG)c | 0.99 | 0.03–39.19 | 72.0 | |
Maternal hysterectomy | 2 | 18,662 | Binary (37 + 38 WG vs. ≥39 WG)c | 1.10 | 0.03–39.35 | 0.0 | |
Maternal blood transfusion | 2 | 15,162 | Binary (37 + 38 WG vs. ≥39 WG)c | 1.21 | 0.02–65.67 | 30.0 | |
Meta-analyses of subgroups | |||||||
 NICU admission only ERCS | 4 | 792,107 | Linear dose-responsea | 0.66 | 0.65–0.67 | 0.0 | |
 NICU death only repeat CS | 2 | 497,917 | U-Shapeb | < 39 0.67 ≥39 1.68 | 0.51–0.87 1.07–2.65 | 0.0 |