Normal fertilisation rates and serum 25-OHD levels among couples undergoing in-vitro fertilisation: a prospective cohort study

Table 4 Binary logistic regression analysis between 25-OHD quartiles and low fertilisation rate

	OR	95%CI	P value
Female 25-OHD group
Group A	4.814	1.266, 18.309	0.020^*
Group B	3.204	0.949, 10.812	0.061
Group C	REF
Male 25-OHD group
Group A	0.520	0.164, 1.643	0.265
Group B	0.981	0.431, 2.235	0.964
Group C	REF
Female age (y)	0.953	0.860, 1.058	0.953
Male age (y)	1.050	0.968, 1.140	0.238
PR (%)	1.001	0.979, 1.024	0.924
Baseline FSH (mIU/ml)	1.006	0.766, 1.322	0.965
Primary infertility
No	REF
Yes	1.023	0.542, 1.932	0.944
Duration of infertility (y)	1.084	0.977, 1.202	0.130
BMI (kg/m2)	1.044	0.933, 1.168	0.455
Stimulation protocol
GnRH-ant	REF
GnRH-a prolonged	1.324	0.563, 3.116	0.520
GnRH-a long	1.502	0.570, 3.955	0.410
Daily dose of gonadotrophins (IU)	0.920	0.644, 1.315	0.648
Number of oocytes retrieved	0.946	0.891, 1.004	0.067

Table 4 depicts the binary logistic regression analysis results of serum 25-OHD levels in couples and normal fertilisation rates (LFR). Normal fertilisation rate > 0.2 (without LFR) was set as response, and normal fertilisation rate < 0.2 (with LFR) was set as reference. The symbol "*" meant that the ORs for exhibiting low fertilisation rate were 4.814 in Group A (95% CI, 1.266–18.309, P = 0.021) compared with Group C

ISSN: 1471-2393