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Table 2 Secondary outcomes

From: The ED50 and ED95 of oxytocin infusion rate for maintaining uterine tone during elective caesarean delivery: a dose-finding study

 

0 IU h− 1

1 IU h− 1

2 IU h− 1

3 IU h− 1

5 IU h− 1

8 IU h− 1

P value

Estimated blood loss (ml)

693 ± 426

701 ± 394

619 ± 322

631 ± 404

625 ± 472

658 ± 330

0.977

Intravenous crystalloid (ml)

900 ± 210

993 ± 283

992 ± 273

1004 ± 296

1024 ± 255

984 ± 206

0.622

Hb in PACU (g dL− 1)

10.7 ± 1.0

10.8 ± 1.3

10.5 ± 0.9

10.9 ± 1.1

10.8 ± 1.2

10.7 ± 0.9

0.864

HCT in PACU (%)

32.4 ± 2.8

32.2 ± 3.8

31.7 ± 2.9

32.5 ± 3.1

31.9 ± 3.4

32.1 ± 2.5

0.956

Hb on postoperative day 1 (g dL− 1)

11.5 ± 1.1

11.3 ± 1.5

11.3 ± 1.1

11.8 ± 1.3

11.1 ± 1.1

11.6 ± 1.0

0.354

HCT on postoperative day 1 (%)

34.0 ± 3.0

33.3 ± 4.3

33.5 ± 3.0

34.7 ± 3.5

32.6 ± 2.9

34.2 ± 2.7

0.303

Rescue oxytocin required [n (%)]

13 (52)

12 (52)

7 (29)

4 (17) a

3 (12)b

2 (8)c

0.000

Secondary uterotonic agents required [n (%)]

6 (24)

1 (4)

1 (4)

0 (0)d

0 (0)e

0 (0)f

0.000

  1. Data are expressed as mean ± SD or n (%). Compared with 0 IU h–1 oxytocin infusion group, fewer patients in the 3, 5, and 8 IU h–1 oxytocin groups needed rescue oxytocin bolus (52% vs 17, 12, and 8%; aP = 0.012, b0.002, and c0.001, respectively) or secondary uterotonic agents (24% vs 0, 0, and 0%; dP = 0.023, e0.022, and f0.022, respectively). PACU postanesthetic care unit, Hb hemoglobin, HCT hematocrit