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Table 5 Univariate and Multivariate analysis of Mode of delivery in TOLAC

From: Effect of epidural analgesia in trial of labor after cesarean on maternal and neonatal outcomes in China: a multicenter, prospective cohort study

Variable

Univariate

Multivariate(n = 354)

P

OR (95%CI)

P

OR (95%CI)

Epidural analgesia

< 0.001

2.614(1.620–4.248)

0.006

2.590(1.315–5.165)

Hospital name

 MCH

 

1(reference)

 

1(reference)

 BA

0.473

1.340(0.623–3.197)

0.141

2.253(0.799–7.068)

 LG

< 0.001

0.214(0.115–0.396)

< 0.001

0.138(0.046–0.391)

General information

 Age (y)

0.015

0.921(0.861–0.983)

< 0.001

0.853(0.774–0.933)

 Gestational age (day)

0.421

0.990(0.965–1.011)

  

 BMI (kg/m2)

0.129

0.944(0.875–1.018)

  

 Maternal education > 12 y

0.187

0.681(0.375–1.184)

  

 Husband education > 12 y

0.114

0.604(0.312–1.099)

  

 Housewives

0.193

2.036(0.776–7.000)

  

History of pregnancy and childbirth

 History of previous vaginal delivery

0.615

0.796(0.343–2.076)

  

Gravidity time (times)

 2

 

1 (reference)

  

 3

0.78

1.076(0.641–1.804)

  

 > 3

0.971

1.013(0.514–2.083)

  

Time from last cesarean section (year)

 ≤ 3

 

1(reference)

  

 3–5

0.246

2.282(0.477–8.592)

  

 > 5

0.923

1.071(0.223–4.046)

  

Progress of Labor in previous caesarean section (cervical dilation: cm)

 0

 

1(reference)

  

 < 3

0.029

1.882(1.083–3.381)

  

 ≥ 3

0.148

1.827(0.844–4.417)

  

 10

0.062

6.942(1.391–126.155)

  

 Cervical score at admission (score)

0.003

1.203(1.066–1.360)

< 0.001

1.421(1.177–1.727)

 Cervical dilation at admission (cm) ≥3

0.021

2.629(1.232–6.513)

0.058

2.698(1.026–8.200)

 Effacement

0.027

1.750(1.062–2.865)

  

 The onset of labor: Spontaneous

< 0.001

7.428(3.484–16.431)

0.002

6.801(2.093–23.518)

 Oxytocin during labor

0.044

0.451(0.211–1.011)

  

 HGB (g/L:115–150)

0.843

0.998(0.981–1.018)

  

 PLT (125–350)

0.924

1.000(0.996–1.005)

  

Labor duration

 The first labor duration (min)

0.553

1.003(0.996–1.018)

  

 The second labor duration (min)

0.37

1.157(0.983–1.945)

  

 The third labor duration (min)

0.859

0.970(0.771–1.779)

  

Neonatal

 Weight (g) ≥3500

0.015

0.512(0.301–0.884)

0.003

0.360(0.183–0.711)

  1. OR Odds ratio, CI Confidence interval;
  2. Multivariable logistic regression included entered factors variable as p < 0.05 (Epidural analgesia, Hospital, Age, Progress of Labor in previous caesarean section, Cervical score at admission, cervical dilation at admission, effacement, the onset of labor: Spontaneous, Oxytocin during labor, Neonatal Weight) and using stepwise regression by AIC criteria. Hosmer-Lemeshow goodness of fit (GOF) test: Chi-squared = 8.034, df = 8, P value = 0.430 McFadden’s pseudo-R squared =0.249 Cox & Snell pseudo-R squared = 0.223 Nagelkerke pseudo-R squared =0.350. All VIFs < 2