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Table 1 Characteristics of studies included in the systematic review and meta-analysis of plasma volume expansion across healthy pregnancy

From: Plasma volume expansion across healthy pregnancy: a systematic review and meta-analysis of longitudinal studies

Author, year Country Sample Size Gravidity Age (y) Height (cm) Weight (kg) Plasma Volume Method No. pregnancy measurements Postpartuma Postpartum plasma volume (mL)
Paintin, 1962 [42] UK 20 1 18-31b 164.4 45.8–78.3b EBD 4 7–8 weeks 2775
Hytten, 1963 [14] UK 39 1 24.9 ± 5.8 162.4 ± 6.1 58.2 ± 5.9 EBD 8 6–8 weeks 2699
Gibson, 1973 [13] UK 9 > 1 28.1 ± 2.9 156.7 ± 3.7 56.8 ± 7.3 EBD 2 3 months 2344
Pirani, 1973 [10] UK 56 1 20.8 155.5 NA EBD 7 6–8 weeks 2545
Taylor, 1979 [41] UK 24 1c 27.1 ± 3.4 163.5 ± 4.9 60.1 ± 8.8 EBD 2 4–6 months 2340
Bruinse, 1985 [46] The Netherlands 37 0.6 ± 0.7d 25.4 ± 3.6 167.1 ± 5.8 61.7 ± 7.9 EBD 3 6 days, 6 weekse, and 6 months 2557
Abudu, 1988 [45] Nigeria 20 1 23.9 ± 5.0 163.0 ± 4.1 58.9 ± 7.9 EBD 2 8 weeks 2165
Pivarnik, 1994 [43] USA 5 NA 29.0 ± 4 159.0 ± 5.0 65.3 ± 4.6 EBD 2 12 weeks 2355
Whittaker, 1996 [15] UK 69 0–3 29.3f NA NA EBD 6 12 weeksg 2382
Vargas, 2007 [44] Bolivia:       CO    
Andean 42 3.4 ± 0.3 27.2 ± 6.4 150.0 ± 0.6 58.8 ± 1.5   2 4 months 2482
European 26 2.3 ± 0.2 32.4 ± 4.0 162.0 ± 1.3 63.5 ± 2.5   2 4 months 2631
  1. Abbreviation: NA not available EBD Evans blue dye, CO CO-rebreathing
  2. Data are mean ± SD unless otherwise specified
  3. aTime from birth
  4. bRange (mean not reported)
  5. cConsists of nulliparous, primiparous and multiparous women
  6. dParity reported
  7. eUsed in the meta-analysis
  8. fAge at delivery
  9. gPrepregnancy value was also reported (2373 mL)