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Table 1 Characteristics of studies included in the systematic review and meta-analysis of plasma volume expansion across healthy pregnancy

From: Plasma volume expansion across healthy pregnancy: a systematic review and meta-analysis of longitudinal studies

Author, year

Country

Sample Size

Gravidity

Age (y)

Height (cm)

Weight (kg)

Plasma Volume Method

No. pregnancy measurements

Postpartuma

Postpartum plasma volume (mL)

Paintin, 1962 [42]

UK

20

1

18-31b

164.4

45.8–78.3b

EBD

4

7–8 weeks

2775

Hytten, 1963 [14]

UK

39

1

24.9 ± 5.8

162.4 ± 6.1

58.2 ± 5.9

EBD

8

6–8 weeks

2699

Gibson, 1973 [13]

UK

9

> 1

28.1 ± 2.9

156.7 ± 3.7

56.8 ± 7.3

EBD

2

3 months

2344

Pirani, 1973 [10]

UK

56

1

20.8

155.5

NA

EBD

7

6–8 weeks

2545

Taylor, 1979 [41]

UK

24

1c

27.1 ± 3.4

163.5 ± 4.9

60.1 ± 8.8

EBD

2

4–6 months

2340

Bruinse, 1985 [46]

The Netherlands

37

0.6 ± 0.7d

25.4 ± 3.6

167.1 ± 5.8

61.7 ± 7.9

EBD

3

6 days, 6 weekse, and 6 months

2557

Abudu, 1988 [45]

Nigeria

20

1

23.9 ± 5.0

163.0 ± 4.1

58.9 ± 7.9

EBD

2

8 weeks

2165

Pivarnik, 1994 [43]

USA

5

NA

29.0 ± 4

159.0 ± 5.0

65.3 ± 4.6

EBD

2

12 weeks

2355

Whittaker, 1996 [15]

UK

69

0–3

29.3f

NA

NA

EBD

6

12 weeksg

2382

Vargas, 2007 [44]

Bolivia:

     

CO

   

Andean

42

3.4 ± 0.3

27.2 ± 6.4

150.0 ± 0.6

58.8 ± 1.5

 

2

4 months

2482

European

26

2.3 ± 0.2

32.4 ± 4.0

162.0 ± 1.3

63.5 ± 2.5

 

2

4 months

2631

  1. Abbreviation: NA not available EBD Evans blue dye, CO CO-rebreathing
  2. Data are mean ± SD unless otherwise specified
  3. aTime from birth
  4. bRange (mean not reported)
  5. cConsists of nulliparous, primiparous and multiparous women
  6. dParity reported
  7. eUsed in the meta-analysis
  8. fAge at delivery
  9. gPrepregnancy value was also reported (2373 mL)