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Table 4 Incidence of birth defects in live-born infants and type of malformations according to the classification from code Q00-Q99 in the international classification of Disease, tenth editon

From: Effects of pre-pregnancy body mass index on pregnancy and perinatal outcomes in women with PCOS undergoing frozen embryo transfer

CharacteristicsNormal (All births n = 635)Overweight (All births n = 296)Obesity(N = 133)Normal vs. OverweightOverweight vs. ObestiyNormal vs. Obesity
Number of birth defects, no. (%)13 (2.05%)2 (0.68%)2 (1.50%)0.1010.3690.507
 Singletons, no (%)10/341 (2.93%)1/144 (0.69%)1/79 (1.27%)0.1210.5860.363
 Multiples, no (%)3/294 (1.02%)1/152 (0.66%)1/54 (1.85%)0.5810.4600.495
Birth defects, by sex
 Male, no (%)7/332 (2.11%)1/141 (0.71%)1/61 (1.64%)0.2630.5170.642
 Female, no (%)6/303 (1.98%)1/155 (0.65%)1/72 (1.39%)0.2570.5370.601
Detailed birth defects
 Q00-Q07 nervous system000///
 Q10-Q18 eye, ear, face, and neck1 (0.16%)000.536/0.363
 Q20-Q28 circulatory system7 (1.10%)02 (1.50%)0.2230.2310.482
 Q30-Q34 respiratory system1 (0.16%)000.536/0.363
 Q35-Q37 cleft lip and cleft palate000///
 Q38-Q45 digestive system02 (0.68%)00.2410.718/
 Q50-Q56 genital organs000///
 Q60-Q64 urinary system3 (0.47%)000.6210.6080.594
 Q65-Q79 musculoskeletal system1 (0.16%)000.536/0.363
 Q80-Q89 other malformations000///
 Q90-Q99 chromosomal abnormalities000///