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Table 4 Incidence of birth defects in live-born infants and type of malformations according to the classification from code Q00-Q99 in the international classification of Disease, tenth editon

From: Effects of pre-pregnancy body mass index on pregnancy and perinatal outcomes in women with PCOS undergoing frozen embryo transfer

Characteristics

Normal (All births n = 635)

Overweight (All births n = 296)

Obesity(N = 133)

Normal vs. Overweight

Overweight vs. Obestiy

Normal vs. Obesity

Number of birth defects, no. (%)

13 (2.05%)

2 (0.68%)

2 (1.50%)

0.101

0.369

0.507

 Singletons, no (%)

10/341 (2.93%)

1/144 (0.69%)

1/79 (1.27%)

0.121

0.586

0.363

 Multiples, no (%)

3/294 (1.02%)

1/152 (0.66%)

1/54 (1.85%)

0.581

0.460

0.495

Birth defects, by sex

 Male, no (%)

7/332 (2.11%)

1/141 (0.71%)

1/61 (1.64%)

0.263

0.517

0.642

 Female, no (%)

6/303 (1.98%)

1/155 (0.65%)

1/72 (1.39%)

0.257

0.537

0.601

Detailed birth defects

 Q00-Q07 nervous system

0

0

0

/

/

/

 Q10-Q18 eye, ear, face, and neck

1 (0.16%)

0

0

0.536

/

0.363

 Q20-Q28 circulatory system

7 (1.10%)

0

2 (1.50%)

0.223

0.231

0.482

 Q30-Q34 respiratory system

1 (0.16%)

0

0

0.536

/

0.363

 Q35-Q37 cleft lip and cleft palate

0

0

0

/

/

/

 Q38-Q45 digestive system

0

2 (0.68%)

0

0.241

0.718

/

 Q50-Q56 genital organs

0

0

0

/

/

/

 Q60-Q64 urinary system

3 (0.47%)

0

0

0.621

0.608

0.594

 Q65-Q79 musculoskeletal system

1 (0.16%)

0

0

0.536

/

0.363

 Q80-Q89 other malformations

0

0

0

/

/

/

 Q90-Q99 chromosomal abnormalities

0

0

0

/

/

/