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Table 3 Antidiabetic Drug use, by maternal age, in all livebirth pregnancies during 2001–2013 in the MSDD

From: Use of Antidiabetic drugs during pregnancy among U.S. women with Livebirth deliveries in the Mini-Sentinel system

 < 20 years20–24 years25–29 years30–34 years35–39 years40–44 years45–54 years
Total unique pregnancies115,584 (100%)260,013 (100%)495,250 (100%)610,703 (100%)329,080 (100%)76,995 (100%)7979 (100%)
Drug product/Class
 Any Antidiabetic Drug1004 (0.87%)5227 (2.01%)18,775 (3.79%)30,327 (4.97%)20,788 (6.32%)5874 (7.63%)681 (8.53%)
 Alpha-Glucosidase Inhibitors4 (0.00%)10 (0.00%)31 (0.01%)54 (0.01%)30 (0.01%)18 (0.02%)2 (0.03%)
 Amylin Analog1 (0.00%)4 (0.00%)15 (0.00%)19 (0.00%)6 (0.00%)3 (0.00%)0 (0.00%)
 Metformin294 (0.25%)1839 (0.71%)8616 (1.74%)12,809 (2.10%)7238 (2.20%)1687 (2.19%)274 (3.43%)
 Dipeptidyl Peptidase-4 Inhibitors1 (0.00%)4 (0.00%)34 (0.01%)69 (0.01%)83 (0.03%)30 (0.04%)21 (0.26%)
 Glucagon-like Peptide-1 Receptor Agonists4 (0.00%)12 (0.00%)58 (0.01%)109 (0.02%)98 (0.03%)36 (0.05%)16 (0.20%)
 Meglitinide Analogs1 (0.00%)8 (0.00%)8 (0.00%)13 (0.00%)9 (0.00%)3 (0.00%)2 (0.03%)
 Sulfonylureas237 (0.21%)1452 (0.56%)5542 (1.12%)10,151 (1.66%)8012 (2.43%)2570 (3.34%)276 (3.46%)
 Thiazolidinediones17 (0.01%)69 (0.03%)208 (0.04%)268 (0.04%)196 (0.06%)73 (0.09%)43 (0.54%)
 Combination Products10 (0.01%)55 (0.02%)117 (0.02%)197 (0.03%)177 (0.05%)52 (0.07%)25 (0.31%)
 Insulin590 (0.51%)2562 (0.99%)6986 (1.41%)11,868 (1.94%)9392 (2.85%)2813 (3.65%)265 (3.32%)