Table 1 Population characteristics
Characteristics | 1st trimester n = 159 | 2nd trimester n = 159 | Total n = 159 | ||||
|---|---|---|---|---|---|---|---|
No ART n = 50 | PI n = 89 | Other regimens n = 20 | No ART n = 6 | PI n = 131 | Other regimens n = 22 |  | |
Maternal age at delivery, years, mean ± SD | 31.7 ± 5.3 | 33.1 ± 4.9 | 31.3 ± 5.0 | 29.7 ± 3.0 | 32.5 ± 5.1 | 32.3 ± 5.4 | 32.4 ± 5.1 |
Ethnicity, n (%) | |||||||
 Afro-Caribbean | 43 (86.0) | 69 (77.5) | 18 (90.0) | 6 (100.0) | 103 (78.6) | 21 (95.5) | 130 (81.8) |
 Caucasian | 7 (14.0) | 17 (19.1) | 1 (5.0) | 0 (0.0) | 24 (18.3) | 1 (4.5) | 25 (15.7) |
 Other | 0 (0.0) | 3 (3.4) | 1 (5.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 4 (2.5) |
BMI, kg/m2, median [IQR] | 27.2 [24.9–31.0] | 25.8 [22.8–29.9] | 26.5 [22.9–30.3] | 28.2 [24.4–34.9] | 26.4 [23.6–30.4] | 24.9 [23.2–28.7] | 26.3 [23.5–30.2] |
Parity, n (%) | |||||||
 0 | 15 (30.0) | 31 (34.8) | 6 (30.0) | 2 (33.3) | 41 (31.3) | 9 (40.9) | 52 (32.7) |
 1 | 18 (36.0) | 31 (34.8) | 10 (50.0) | 4 (66.7) | 45 (34.4) | 10 (45.5) | 59 (37.1) |
 2 | 12 (24.0) | 14 (15.7) | 1 (5.0) | 0 (0.0) | 26 (19.8) | 1 (4.5) | 27 (17.0) |
 3 and more | 5 (10) | 13 (14.7) | 3 (15.0) | 0 (0.0) | 19 (14.5) | 2 (9.1) | 21 (13.2) |
Smoker, n (%) | 6 (12.0) | 8 (9.0) | 1 (5.0) | 0 (0.0) | 6 (4.6) | 0 (0.0) | Â |
Chronic hypertension, n (%) | 2 (4.0) | 1 (1.1) | 0 (0.0) | 0 (0.0) | 3 (2.3) | 0 (0.0) | 3 (1.9) |
Gestational hypertension or preeclampsia, n (%) | 4 (8.0) | 9 (10.1) | 2 (10.0) | 1 (16.7) | 11 (7.2) | 3 (13.6) | 15 (9.4) |
Sex of fetus, n (%) | |||||||
 Male | 25 (50.0) | 53 (59.6) | 4 (20.0) | 1 (16.7) | 76 (58.0) | 5 (22.7) | 82 (51.6) |
CD4 counta, median [IQR] | |||||||
 Total/mm3 | 495.5 [270.0–679.5] | 573.5 [404.25–751.5] | 580.5 [372.5–733.5] | 493.5 [193.5–859.5] | 561.0 [378.5–722.5] | 645.0 [470.75–1056.0] |  |
 Percentage | 25.0 [16.0–33.0] | 32.0 [25.0–38.5] | 33.5 [23.0–43.5] | 26.0 [17.0–37.0] | 31.0 [24.0–39.0] | 40.0 [27.0–44.0] |  |
Undetectable viral loada, n (%) | 4 (8.0) | 72 (80.9) | 16 (80.0) | 2 (33.3) | 94 (71.8) | 19 (86.4) | Â |
Pregnancy outcome, n (%) | |||||||
 SGA | 8 (16.0) | 19 (21.3) | 2 (10.0) | 1 (16.7) | 26 (19.8) | 2 (9.1) | 29 (18.6) |
 Preterm birth | 6 (12.0) | 17 (19.1) | 2 (10.0) | 0 (0.0) | 22 (16.8) | 3 (13.6) | 25 (15.7) |
Gestationnal agea weeks, median [IQR] | 9.7 [7.9–11.9] | 10.7 [8.9–11.9] | 10.7 [7.9–11.8] | 18.3 [15.8–19.1] | 19.6 [17.1–21.3] | 19.3 [17.1–23.0] |  |