Skip to main content

Table 4 Placental protein expression of HTR1A and NPY2R in healthy controls, women with untreated depression and women on antidepressant treatment

From: The effect of antenatal depression and antidepressant treatment on placental tissue: a protein-validated gene expression study

 

Healthy controls

(n 37)

Women with untreated depression

(n 13)

Women on antidepressant treatment

(n 21)

p

HTR1A

 Trophoblasts

238 (206–263)

225 (213–244)

263 (238–288)

0.017

 Endothelial cells

225 (175–238)

225 (169–263)

225 (206–263)

0.284

 Stroma cells

175 (138–213)

175 (156–194)

175 (175–231)

0.258

NPY2R

 Trophoblasts

188 (156–213)

213 (163–225)

200 (163–238)

0.743

 Endothelial cells

63 (50–63)

63 (50–113)

50 (50–81)

0.351

 Stroma cells

50 (50–63)

63 (50–113)

50 (50–81)

0.370

  1. Data presented as median H-score (IQR). Statistics by Kruskal-Wallis test