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Table 3 Associations of maternal social supports and stressful life events with VSD in offspring

From: Associations between maternal social support and stressful life event with ventricular septal defect in offspring: a case-control study

 Before Propensity Score MatchingAfter Propensity Score Matching
Controls
n = 262
Cases
n = 202
Crude Model
OR (95% CI)
Adjust Model
aOR (95% CI)
Controls
n = 168
Cases
n = 202
OR (95% CI)
Social support index
 0–4 (Low)68761145761
 5–7 (Medium high)95670.631 (0.401, 0.992) *0.523 (0.283, 0.967) *64670.620 (0.375, 1.025)
 8 (High)99560.533 (0.337, 0.844) **0.510 (0.321, 0.854) *59560.592 (0.353, 0.992) *
Stressful life event index
 0 (Low)167111111061111
 1 (Medium high)60481.204 (0.768, 1.886)1.190 (0.643, 2.201)40481.146 (0.697, 1.884)
  ≥ 2 (High)26392.257 (1.300, 3.916) **2.342 (1.138, 4.819) *16392.328 (1.228, 4.414) **
Stressful Life event with social supporta
 Low stress & High support1781081 1131081
 Low stress & Low support49511.715 (1.084, 2.715) *2.059 (1.104, 3.841) *33511.617 (0.970, 2.696)
 High stress & High support13172.155 (1.007, 4.612) *2.699 (1.042, 6.988) *8172.223 (0.922, 5.364)
 High stress & Low support13222.789 (1.349, 5.765) *2.781 (1.033, 7.489) *8222.877 (1.228, 6.739) *
  1. Adjusted Model: adjusted for maternal ethic, maternal age at delivery, maternal education, marital status, residence, maternal prepregnancy obesity, multiple births, infant gender, and family history of CHD, maternal smoking/drinking, maternal diabetes/hypertension, maternal folic acid supplementation
  2. aOR adjusted odds ratio CI confidence interval OR odds ratio VSD Ventricular septal defect
  3. a Women were designated as having low event if the life events index score was 0–1 and as having high event if it was ≥2. Women were designated as having low social support if the social support index was 0–4 and as having high support if it was ≥5
  4. * p value < 0.05; ** p value < 0.01