|
Objectives
|
1
|
State specific objectives, including any pre-specified hypotheses
|
2
|
2
|
2
|
2
|
2
|
1
|
2
|
2
|
2
|
2
|
2
|
|
Methods
|
|
Study design
|
2
|
Present key elements of study design early in the paper
|
2
|
2
|
1
|
1
|
2
|
1
|
2
|
1
|
2
|
1
|
1
|
|
Setting
|
3
|
Describe the setting, locations, and relevant dates, including periods of recruitment, exposure, follow-up, and data collection
|
2
|
1
|
2
|
2
|
2
|
2
|
1
|
2
|
2
|
2
|
2
|
|
Participants
|
4
|
Give the eligibility criteria, and the sources and methods of selection of participants
|
2
|
1
|
1
|
2
|
2
|
1
|
2
|
1
|
2
|
2
|
2
|
|
Variables
|
5
|
Clearly define all outcomes, exposures, predictors, potential confounders, and effect modifiers.
|
2
|
2
|
2
| |
1
|
1
|
2
|
1
| |
1
|
1
|
|
Data sources/ measurement
|
6
|
For each variable of interest, give sources of data and details of methods of assessment (measurement).
|
2
|
2
|
1
|
1
|
2
| |
2
| |
2
|
1
|
1
|
|
Bias
|
7
|
Describe any efforts to address potential sources of bias
|
2
|
1
|
1
| |
1
| |
1
| |
1
|
1
|
1
|
|
Study size
|
8
|
Explain how the study size was arrived at
|
1
| |
1
|
2
|
2
| | |
1
|
1
|
1
|
1
|
|
Quantitative variables
|
9
|
Explain how quantitative variables were handled in the analyses. If applicable, describe which groupings were chosen and why
|
2
|
2
|
2
|
1
|
2
|
1
|
2
|
1
|
2
|
2
|
2
|
|
Statistical methods
|
10
|
Describe all statistical methods, including those used to control for confounding
|
2
|
2
|
2
| |
2
|
1
|
2
|
1
|
1
|
1
|
1
|
| |
11
|
Explain how missing data were addressed
|
1
|
1
|
1
|
1
|
1
|
1
|
1
|
1
| | |
1
|
|
Results
|
|
Participants
|
12
|
Report numbers of participants and study and response rate
|
2
|
1
|
1
| |
2
|
1
|
1
|
1
|
2
|
1
|
1
|
|
Descriptive data
|
13
|
Give characteristics of study participants (eg demographic, clinical, social) and information on exposures and potential confounders
|
2
|
1
|
2
|
1
|
2
|
2
|
2
|
2
|
1
|
2
|
2
|
|
Main results
|
14
|
Give unadjusted estimates and, if applicable, confounder-adjusted estimates and their precision (eg, 95% confidence interval). Make clear which confounders were adjusted for and why they were included
|
2
|
2
|
1
| |
2
|
1
|
2
| |
1
|
1
|
1
|
|
Discussion
|
|
Key Results
|
15
|
Summarise key results with reference to study objectives
|
2
|
2
|
2
| |
2
|
2
|
2
|
1
|
1
|
2
|
1
|
|
Limitations
|
16
|
Discuss limitations of the study, taking into account sources of potential bias or imprecision. Discuss both direction and magnitude of any potential bias
|
2
|
1
|
1
| |
2
|
1
|
1
| |
2
|
1
|
2
|
|
Interpretation
|
17
|
Give a cautious overall interpretation of results considering objectives, limitations, multiplicity of analyses, results from similar studies, and other relevant evidence
|
2
|
1
|
1
|
1
|
2
|
1
|
2
|
2
|
1
|
2
|
2
|
| | |
Quality score
|
32
|
26
|
24
|
16
|
31
|
17
|
27
|
17
|
23
|
23
|
24
|
| | |
% Quality score
|
94
|
77
|
70
|
47
|
91
|
50
|
79
|
50
|
67
|
67
|
70
|
|
Component
|
item
|
Quality criteria description
|
Ochako, 2011
|
Gross, 2012
|
Rai, 2012
|
Rai l, 2013
|
Singh, 2006
|
Rai, 2014
|
Worku, 2016
|
Banke-Thomas.2017
|
Helleringer, 2017
|
Musarandega, 2017
|
Ronen, 2017
|
|
Objectives
|
1
|
State specific objectives, including any pre-specified hypotheses
|
2
|
2
|
2
|
2
|
2
|
2
|
2
|
2
|
2
|
1
|
1
|
|
Methods
|
|
Study design
|
2
|
Present key elements of study design early in the paper
|
2
|
1
|
2
|
1
|
1
|
1
|
1
|
1
|
2
|
2
|
2
|
|
Setting
|
3
|
Describe the setting, locations, and relevant dates, including periods of recruitment, exposure, follow-up, and data collection
|
2
|
2
|
2
|
2
|
1
|
1
|
2
|
2
|
1
|
1
|
2
|
|
Participants
|
4
|
Give the eligibility criteria, and the sources and methods of selection of participants
|
1
|
2
|
2
|
1
|
2
|
1
|
2
|
2
|
2
|
2
|
2
|
|
Variables
|
5
|
Clearly define all outcomes, exposures, predictors, potential confounders, and effect modifiers.
|
1
|
1
|
2
|
2
|
2
|
2
|
1
|
2
|
1
|
2
|
1
|
|
Data sources/ measurement
|
6
|
For each variable of interest, give sources of data and details of methods of assessment (measurement).
|
2
|
1
|
1
|
2
|
1
|
2
|
1
|
2
|
1
|
2
|
1
|
|
Bias
|
7
|
Describe any efforts to address potential sources of bias
|
1
| |
1
|
1
|
1
|
1
|
2
|
2
|
1
| |
1
|
|
Study size
|
8
|
Explain how the study size was arrived at
|
2
|
1
|
2
|
2
|
1
|
2
|
1
|
1
|
2
|
2
|
1
|
|
Quantitative variables
|
9
|
Explain how quantitative variables were handled in the analyses. If applicable, describe which groupings were chosen and why
|
1
| |
2
|
1
|
2
|
2
|
1
|
2
|
1
|
2
|
1
|
|
Statistical methods
|
10
|
Describe all statistical methods, including those used to control for confounding
|
1
|
1
|
1
|
1
|
1
|
2
|
1
|
2
|
1
|
1
|
1
|
| |
11
|
Explain how missing data were addressed
|
1
| |
1
| |
1
| | | | | | |
|
Results
|
|
Participants
|
12
|
Report numbers of participants and study and response rate
|
2
|
2
|
1
|
1
|
2
|
1
|
1
|
1
|
1
|
1
|
1
|
|
Descriptive data
|
13
|
Give characteristics of study participants (eg demographic, clinical, social) and information on exposures and potential confounders
|
2
|
1
|
2
|
2
|
2
|
2
|
2
|
2
|
1
|
2
|
1
|
|
Main results
|
14
|
Give unadjusted estimates and, if applicable, confounder-adjusted estimates and their precision (eg, 95% confidence interval). Make clear which confounders were adjusted for and why they were included
|
1
| |
1
|
1
|
1
|
1
|
1
|
2
|
1
|
1
|
1
|
|
Discussion
|
|
Key results
|
15
|
Summarise key results with reference to study objectives
|
2
|
2
|
2
|
2
|
2
|
1
|
2
|
2
|
2
|
2
|
1
|
|
Limitations
|
16
|
Discuss limitations of the study, taking into account sources of potential bias or imprecision. Discuss both direction and magnitude of any potential bias
|
1
|
1
| |
1
|
1
|
1
|
2
|
1
|
1
|
1
|
1
|
|
Interpretation
|
17
|
Give a cautious overall interpretation of results considering objectives, limitations, multiplicity of analyses, results from similar studies, and other relevant evidence
|
1
|
2
|
2
|
2
|
1
|
2
|
2
|
2
|
1
|
1
|
1
|
| | |
Quality score
|
25
|
19
|
26
|
24
|
24
|
24
|
27
|
29
|
21
|
23
|
19
|
| | |
% Quality score
|
73
|
55
|
76
|
70
|
70
|
70
|
79
|
85
|
61
|
67
|
55
|
