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Table 2 Bleeding characteristics at time of inclusion of women with persistent postpartum haemorrhage, as compared with women with different cut-off values for transfused units of packed red blood cells (RBC) within 24 h following birth. Women with higher numbers of RBCs are included in cohorts of women with fewer units transfused

From: Clinical characteristics of women captured by extending the definition of severe postpartum haemorrhage with ‘refractoriness to treatment’: a cohort study

Bleeding characteristic

Persistent postpartum haemorrhage (N = 1260)

≥4 units RBC (N = 845)

≥6 units RBC (N = 325)

≥8 units RBC (N = 176)

≥10 units RBC (N = 115)

Time from birth till inclusion of patients – no. (%)

 < 1 h

820 (65.1)

37 (4.4)

9 (2.8)

4 (2.3)

2 (1.7)

 ≥ 1–2 h

251 (19.9)

96 (11.4)

41 (12.6)

11 (6.3)

3 (2.6)

 ≥ 2 h

189 (15.0)

712 (84.3)

275 (84.6)

161 (91.5)

110 (95.7)

 Unknown

1 (0.5)

Mode of birth - no. (%)

 Vaginal

967 (76.7)

612 (72.4)

207 (63.7)

100 (56.8)

62 (53.9)

 Caesarean

285 (22.6)

228 (27.0)

116 (35.7)

75 (42.6)

53 (46.1)

 Unknown

8 (0.6)

5 (0.6)

2 (0.6)

1 (0.6)

Cause of haemorrhage – no. (%)

 Uterine atony

805 (63.9)

539 (63.8)

214 (65.8)

107 (60.8)

66 (57.4)

 Retained placenta

219 (17.4)

135 (16.0)

29 (8.9)

18 (10.2)

13 (11.3)

 Abnormally invasive placenta

113 (9.0)

71 (8.4)

26 (8.0)

17 (9.7)

13 (11.3)

 Placenta previa

12 (1.0)

13 (1.5)

6 (1.8)

4 (2.3)

3 (2.6)

 Placental abruption

12 (1.0)

18 (2.1)

11 (3.4)

5 (2.8)

1 (0.9)

 Surgical cause

92 (7.3)

66 (7.8)

36 (11.1)

22 (12.5)

16 (13.9)

 Pre-existent coagulation disorder

7 (0.6)

3 (0.4)

3 (0.9)

3 (1.7)

3 (2.6)

Blood loss – no. (%)

 < 1 L

673 (53.4)

7 (0.8)

1 (0.3)

1 (0.6)

 ≥ 1-2 L

407 (32.3)

82 (9.7)

15 (4.6)

3 (1.7)

2 (1.7)

 ≥ 2 L

180 (14.3)

756 (89.5)

309 (95.1)

172 (97.7)

113 (98.3)

Bleeding rate – no. (%)

 < 1 L/hr.

457 (36.3)

689 (81.5)

24 (74.2)

127 (72.2)

80 (69.6)

 ≥ 1-2 L/hr.

316 (25.1)

100 (11.8)

56 (17.2)

34 (19.3)

21 (18.3)

 ≥ 2 L/hr.

481 (38.2)

41 (4.9)

23 (7.1)

12 (6.8)

12 (10.4)

 Unknown

6 (0.5)

15 (1.8)

5 (1.5)

3 (1.7)

2 (1.7)

Signs of haemorrhagic shock – no. (%)

 No

344 (27.3)

85 (10.1)

23 (7.1)

9 (5.1)

6 (5.2)

 Yes

580 (46.0)

722 (85.4)

288 (88.6)

159 (90.3)

104 (90.4)

 Unknown

336 (26.7)

38 (4.5)

14 (4.3)

8 (4.5)

5 (4.3)