OTTILIA | |
Baseline Clinical information: • Maternal age • Body Mass Index • Smoking habit • Reproductive history (previous pregnancies and obstetric complications occurred) • Personal and family history of VTE • Presence of inherited or acquired thrombophilias • Thrombophilic risk factors Index-pregnancy information: • Results of performed imaging tests, (ultrasonography, Doppler ultrasonography) • Invasive prenatal testing (i.e. villous sampling, amniocentesis) • Antithrombotic prophylaxis (brand, doses/day, duration) | Follow-up Pregnancy outcomes: • Live birth (gestational age, delivery mode, sex, birth weight, fetal or maternal hemorrhage) • Obstetric complications (PL, IUFD, gestational hypertension, preeclampsia, HELLP syndrome, SGA newborns, placental abruption) • VTE |
FIRST | |
Baseline Clinical information: • Maternal age • Body Mass Index • Smoking habit • Reproductive history (previous spontaneous pregnancies, ART attempts) • Cause of infertility (female, male, mixed or idiophatic), • Personal and family history of VTE • Presence of inherited or acquired thrombophilias • Thrombophilic risk factors Index-ART cycle information: • Fertilization (autologous/heterologous) • Type of ART procedure (IUI, IVF, ICSI, Other) • Ovarian stimulation (brand, doses/day, duration) • Antithrombotic prophylaxis (brand, doses/day, duration), • Number of oocytes retrieved •Number of embryo transfers | Follow-up ART outcomes: • Clinical pregnancy • Live birth (gestational age, delivery mode, sex, birth weight, fetal or maternal hemorrhage) • Obstetric complications (PL, IUFD, gestational hypertension, preeclampsia, HELLP syndrome, SGA newborns, placental abruption) • OHSS (time of occurrence after ovarian stimulation, severity, estradiol levels pg/ml, treatment) • VTE |