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Table 2 Baseline and Follow-up data for evaluation and monitoring of women enrolled in the OTTILIA and FIRST registries

From: Rationale and design of two prospective, multicenter, observational studies on reproductive outcome in women with recurrent failures after spontaneous or assisted conception: OTTILIA and FIRST registries

OTTILIA
Baseline
Clinical information:
 • Maternal age
 • Body Mass Index
 • Smoking habit
 • Reproductive history (previous pregnancies and obstetric complications occurred)
 • Personal and family history of VTE
 • Presence of inherited or acquired thrombophilias
 • Thrombophilic risk factors
Index-pregnancy information:
 • Results of performed imaging tests, (ultrasonography, Doppler ultrasonography)
 • Invasive prenatal testing (i.e. villous sampling, amniocentesis)
 • Antithrombotic prophylaxis (brand, doses/day, duration)
Follow-up
Pregnancy outcomes:
• Live birth (gestational age, delivery mode, sex, birth weight, fetal or maternal hemorrhage)
• Obstetric complications (PL, IUFD, gestational hypertension, preeclampsia, HELLP syndrome, SGA newborns, placental abruption)
• VTE
FIRST
Baseline
Clinical information:
 • Maternal age
 • Body Mass Index
 • Smoking habit
 • Reproductive history (previous spontaneous pregnancies, ART attempts)
 • Cause of infertility (female, male, mixed or idiophatic),
 • Personal and family history of VTE
 • Presence of inherited or acquired thrombophilias
 • Thrombophilic risk factors
Index-ART cycle information:
 • Fertilization (autologous/heterologous)
 • Type of ART procedure (IUI, IVF, ICSI, Other)
 • Ovarian stimulation (brand, doses/day, duration)
 • Antithrombotic prophylaxis (brand, doses/day, duration),
 • Number of oocytes retrieved
 •Number of embryo transfers
Follow-up
ART outcomes:
• Clinical pregnancy
• Live birth (gestational age, delivery mode, sex, birth weight, fetal or maternal hemorrhage)
• Obstetric complications (PL, IUFD, gestational hypertension, preeclampsia, HELLP syndrome, SGA newborns, placental abruption)
• OHSS (time of occurrence after ovarian stimulation, severity, estradiol levels pg/ml, treatment)
• VTE
  1. VTE venous thromboembolism, IUI intrauterine insemination, IVF in vitro fertilization, ICSI intracytoplasmic sperm injection, PL pregnancy loss, IUFD intrauterine fetal death, SGA small-for-gestational age, OHSS ovarian hyperstimulation syndrome