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Table 3 Odds ratios of gestational weight gain during second pregnancy associated with GDM

From: Weight retention at six weeks postpartum and the risk of gestational diabetes mellitus in a second pregnancy

  Number of GDM in the second pregnancy Unadjusted OR (95% CI) Adjusted*#
OR (95% CI) β value SE Wald χ2 P
All women*
 Gestational weight gain during the second pregnancy
  Inadequate 485 1.65(1.41~1.91) 1.67(1.43~1.93) 0.51 0.08 44.49 < 0.001
  Adequate 365 1 1 / / / /
  Excessive 248 1.04(0.87~1.23) 1.04(0.88~1.24) 0.05 0.09 0.26 0.610
BMI (kg/m2) in the first pregnancy < 25#
 Gestational weight gain during the second pregnancy
  Inadequate 374 1.69(1.42~2.00) 1.69(1.42~2.01) 0.53 0.09 35.61 < 0.001
  Adequate 274 1 1 / / / /
  Excessive 189 1.06(0.87~1.30) 1.09(0.89~1.34) 0.09 0.10 0.71 0.401
BMI in the first pregnancy ≥25#
 Gestational weight gain during the second pregnancy
  Inadequate 111 1.53(1.13~2.07) 1.54(1.14~2.09) 0.43 0.16 7.72 0.005
  Adequate 91 1 1 / / / /
  Excessive 59 0.96(0.67~1.36) 0.94(0.66~1.34) −0.06 0.18 0.10 0.752
  1. BMI, body mass index; GDM, gestational diabetes mellitus; OR, odds ratio; SE, standard error
  2. * Model adjusted for interpregnancy interval, BMI in the first pregnancy, interpregnancy BMI change, and BMI change at six weeks postpartum after the first pregnancy
  3. # Model adjusted for interpregnancy interval, interpregnancy BMI change, and BMI change at six weeks postpartum after the first pregnancy