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Table 2 Odds ratios of interpregnancy BMI change associated with GDM in the second pregnancy

From: Weight retention at six weeks postpartum and the risk of gestational diabetes mellitus in a second pregnancy

  Number of GDM in the second pregnancy Unadjusted OR (95% CI) Adjusted OR (95% CI)*#
All women*
 Interpregnancy BMI (kg/m2) change
  Lost 1.0 or more 31 0.36(0.25~0.54) 0.28 (0.19~0.43)
  Remain stable (±1.0) 476 1.00 1.00
  Gained 1.0–1.9 237 1.75 (1.47~2.08) 1.77 (1.49~2.11)
  Gained 2.0–2.9 159 1.76 (1.44~2.15) 1.79 (1.46~2.19)
  Gained 3.0 or more 195 1.88 (1.56~2.27) 1.80 (1.49~2.17)
BMI in the first pregnancy < 25#
 Interpregnancy BMI change
  Lost 1.0 or more 26 1.05 (0.68~1.61) 1.01 (0.66~1.56)
  Remain stable (±1.0) 375 1.00 1.00
  Gained 1.0–1.9 183 1.82 (1.50~2.22) 1.89 (1.55~2.31)
  Gained 2.0–2.9 113 1.84 (1.46~2.34) 1.91 (1.50~2.42)
  Gained 3.0 or more 140 1.97 (1.58~2.45) 1.93 (1.55~2.41)
BMI in the first pregnancy ≥25#
 Interpregnancy BMI change
  Lost 1.0 or more 5 0.08 (0.03~0.19) 0.08 (0.03~0.19)
  Remain stable (±1.0) 101 1 1
  Gained 1.0–1.9 54 1.50 (1.04~2.17) 1.51 (1.04~2.18)
  Gained 2.0–2.9 46 1.51 (1.02~2.23) 1.51 (1.02~2.23)
  Gained 3.0 or more 55 1.61 (1.11~2.33) 1.62 (1.12~2.34)
  1. BMI, Body mass index; GDM, Gestational diabetes mellitus; OR, Odds ratio
  2. * Model adjusted for interpregnancy interval, BMI in the first pregnancy, gestational weight gain during 2nd pregnancy, and BMI change at six weeks postpartum after the first pregnancy
  3. # Model adjusted for interpregnancy interval, gestational weight gain during 2nd pregnancy, and BMI change at six weeks postpartum after the first pregnancy