Table 3 Prediction performance of the different diagnostic methods for respective outcomes
Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | LR+ (95% CI) | LR− | |
|---|---|---|---|---|---|---|
Delivery within 7 days (frequency 15/85), the number of positive results: fFN = 8, CL = 8, combination test = 6 | ||||||
fFN | (53.3) (30.1–75.3) | 67.1 (54.9–77.9) | 25.8 (16.3–38.3) | 87.0 (79.2–92.2) | 1.6 (0.9–2.9) | 0.7 (0.4–1.2) |
CL | 53.3 (26.6–78.7) | 48.6 (36.4–60.9) | 18.2 (11.6–27.3) | 90.2 (72.9–89.8) | 1.0 (0.6–1.8) | 0.9 (0.5–1.7) |
Combination test | 40.0 (16.3–67.7 | 75.7 (63.9–85.2) | 26.1 (14.4–42.6) | 85.5 (79.2–90.1) | 1.6 (0.7–3.5) | 0.8 (0.5–1.2) |
Delivery within 14 days (frequency 17/85), the number of positive results: fFN = 9, CL = 9, combination test = 6 | ||||||
fFN | 52.9 (27.8–77.0) | 67.6 (55.2–78.5) | 29.0 (18.9–41.8) | 85.2 (77.2–90.7) | 1.6 (0.9–2.8) | 0.7 (0.4–1.2) |
CL | 52.9 (27.8–77.0) | 48.5 (36.2–61.0) | 20.5 (13.4–29.9) | 80.5 (70.2–87.8) | 1.0 (0.6–1.7) | 0.9 (0.1–1.7) |
Combination test | 35.3 (14.2–61.7) | 75.0 (63.0–84.7) | 26.1 (14.1–43.1) | 82.3(76.1–87.1) | 1.4 (0.7–3.0) | 0.9 (0.6–1.3) |
Delivery at < 34 weeks (frequency 20/85), the number of positive results: fFN = 10, CL = 13, combination test = 9 | ||||||
fFN | 50.0 (27.2–72.8) | 67.7 (54.9–78.8) | 32.3 (21.4–45.5) | 81.5 (73.4–87.6) | 1.5 (0.8–2.7) | 0.7 (0.5–1.2) |
CL | 65.0 (40.8–84.6) | 52.3 (39.5–64.9) | 29.5 (21.7–38.7) | 82.9 (71.9–90.2) | 1.4 (0.9–2.1) | 0.7 (0.3–1.3) |
Combination test | 45.0 (23.1–68.5) | 78.5 (66.5–87.7) | 39.1 (24.7–55.7) | 82.3 (75.3–87.5) | 2.1 (1.1–4.1) | 0.7 (0.5–1.1) |
Delivery at < 37 weeks (frequency 42/85), the number of positive results: fFN = 20, CL = 26, combination test = 16 | ||||||
fFN | 47.6 (32.0–63.6) | 74.4 (58.5–86.5) | 64.5 (49.9–76.8) | 59.3 (51.0–67.1) | 1.9 (1.0–3.4) | 0.7 (0.5–0.9) |
CL | 61.9 (45.6–76.4) | 58.1 (42.1–72.9) | 59.1 (48.6–68.8) | 61.0 (49.6–71.3) | 1.5 (1.0–2.3) | 0.7 (0.4–1.0) |
Combination test | 38.1 (23.6–54.4) | 83.7 (69.3–93.2) | 69.6 (51.2–83.3) | 58.1 (51.4–64.5) | 2.3 (1.1–5.1) | 0.7 (0.5–0.9) |