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Table 3 Association between fetal anemia, preterm delivery, and Sociodemographic, obstetric and clinical characteristics of 631 pregnant women

From: Adverse birth outcomes among mothers who received intermittent preventive treatment with Sulphadoxine-Pyrimethamine in the low malaria transmission region

 

Foetal Anemia

OR (95% CI)

p-value

Preterm delivery

Yes

37 (%)

No

594 (%)

Yes

No

OR (95%CI)

p-value

AOR (95%CI)

p-value

Variable

Age groups

 18–24

12 (32.4)

266 (44.8)

0.5 (0.17–1.47)

0.21

31 (11.2)

245 (88.8)

1.4 (0.53–3.81)

0.49

  

 25–29

10 (27.0)

167 (28.1)

0.7 (0.22–2.01)

0.46

13 (7.3)

166 (92.7)

0.88 (0.30–2.57)

0.81

  

 30–34

10 (27.0)

106 (17.8)

1.0 (0.34–3.19)

0.95

9 (7.8)

106 (92.2)

0.95 (0.30–2.97)

0.93

  

 > 34

5 (13.5)

55 (9.3)

1

 

5 (8.2)

56 (91.8)

1

   

Marital status

 Unmarried

6 (16.2)

151 (25.4)

0.6 (0.23–1.39)

0.21

11 (7.0)

146 (93.0)

0.68 (0.35–1.36)

0.28

  

 Married

31 (83.8)

443 (74.6)

1

 

47 (9.9)

427 (90.1)

1

   

Education level

 No formal education

3 (8.1)

22 (3.7)

2.5 (0.24–25.67)

0.45

0 (0.0)

25 (100)

0.0

1

  

 Primary education

25 (67.6)

341 (57.4)

1.3 (0.17–10.29)

0.80

32 (8.7)

334 (91.3)

0.51 (0.14–1.85)

0.31

  

 Secondary education

8 (21.6)

213 (35.9)

0.7 (0.08–5.71)

0.72

23 (10.4)

198 (89.6)

0.62 (0.17–2.29)

0.47

  

 Tertiary education

1 (2.7)

18 (3.0)

1

 

3 (15.8)

16 (84.2)

1

   

Attendance to ANC

 < 4

11 (29.7)

210 (35.4)

0.8 (0.38–1.60)

0.49

24 (10.6)

202 (89.4)

1.3 (0.75–2.25)

0.36

  

 ≥ 4

26 (70.3)

384 (64.6)

1

 

34 (8.4)

371 (91.6)

1

   

FEFO use

 No

3 (8.1)

15 (2.5)

3.4 (0.94–12.34)

0.06

0 (0.0)

18 (100.0)

0.0 (0.0)

1

  

 Yes

34 (91.9)

579 (97.5)

1

 

58 (9.5)

555 (90.5)

1

   

Mebendazole use

 No

2 (5.4)

33 (5.6)

1.0 (0.22–4.22)

0.97

3 (8.6)

32 (91.4)

0.92 (0.27–3.11)

0.90

  

 Yes

35 (94.6)

561 (94.4)

1

 

55 (9.2)

541 (90.8)

1

   

Gravidity

 Primigravida

12 (32.4)

231 (38.9)

0.7 (0.34–1.65)

0.5

31 (12.8)

212 (87.2)

1.95 (1.02–3.72)

0.043

1.97 (1.01–3.81)

0.045

 Secundigravida

11 (29.7)

162 (27.3)

1.0 (0.43–2.21)

1.0

12 (6.9)

161 (93.1)

0.99 (0.45–2.18)

0.99

0.95 (0.43–2.13)

0.91

 Multigravida

14 (37.8)

201 (33.8)

1

 

15 (7.0)

200 (93.0)

1

 

1

 

IPTp-SP doses taken

 0

0 (0.0)

14 (2.4)

0

1.0

0 (0.0)

14 (100.0)

0.0 (0.0)

1

0.0 (0.0)

1

 1

6 (16.2)

64 (10.8)

1.7 (0.65–4.34)

0.29

11 (15.7)

59 (84.3)

1.89 (0.91–3.93)

0.09

1.87 (0.87–4.02)

0.11

 2

11 (29.7)

158 (26.6)

1.2 (0.58–2.66)

0.57

13 (7.7)

156 (92.3)

0.84 (0.43–1.64)

0.62

0.83 (0.42–1.63)

0.58

 ≥ 3

20 (54.1)

358 (60.3)

1

 

34 (9.0)

344 (91.0)

1

 

1

 

Malaria by MRDT

 Positive

0 (0.0)

4 (0.7)

–

1.0

0 (0.0)

4 (100.0)

0.0 (0.0)

1

  

 Negative

37 (100.0)

590 (99.3)

–

 

58 (9.3)

569 (90.7)

1

   

ITN use

 Yes

37 (100)

582 (98.0)

1

 

55 (8.9)

564 (91.1)

1

 

1

 

 No

0 (0.0)

12 (2.0)

0.0 (0.0)

1

3 (25.0)

9 (75.0)

3.4 (0.90–13.0)

0.07

3.31 (0.84–13.03)

0.09

IRS use

 Yes

21 (56.8)

373 (62.8)

1

 

43 (10.9)

351 (89.1)

1

 

1

 

 No

16 (43.2)

221 (37.2)

1.29 (0.66–2.52)

0.46

15 (6.3)

222 (93.7)

0.55 (0.30–1.02)

0.06

0.50 (0.27–0.95)

0.03

Maternal anemia

 Non-anemia (≥11.0 g/dL)

18 (48.6)

356 (59.9)

1

 

3 (33.3)

6 (66.7)

1

 

1

 

 Mild anemia (10–10.9 g/dL)

12 (32.4)

133 (22.4)

1.8 (0.837–3.805)

0.13

11 (10.7)

92 (89.3)

0.85 (0.42–1.73)

0.65

0.78 (0.38–1.62)

0.50

 Moderate anemia (7.0–9.9 g/dL)

6 (16.2)

97 (16.3)

1.2 (0.473–3.166)

0.68

11 (7.6)

134 (92.4)

1.24 (0.60–2.54)

0.57

1.25 (0.59–2.62)

0.56

 Severe anemia (< 7.0 g/dL)

1 (2.7)

8 (1.3)

2.5 (0.293–20.847)

0.41

33 (8.8)

341 (91.2)

5.17 (1.24–21.62)

0.025

6.5 (1.49–28.16)

0.013

  1. Adjusted for gravidity, ITN use, IRS use, IPTp-SP use and maternal anemia