Table 2 Hematological and cytokine parameters in HDP, in normotensive pregnant women and in non-pregnant women
Variable | Normotensive pregnant women (n = 77) | Hypertensive pregnant women (n = 76) | Non pregnant women [17] | P value |
|---|---|---|---|---|
RBC count and RBC’s indices | ||||
 Mean RBC (SD) | 3.85((0.41) | 3.75 (0.66) | 4.69 (3.84,5.59) | 0.264 |
 Mean Hb ± (SD) | 10.99 (1.09) | 10.06 (2.21) | 13.5 (11.1,15.7) | 0.001 |
 Mean MCHC ± (SD) | 32.06 (0.76) | 31.77 (1.04) | 32.7 (30.4,34.8) | 0.051 |
 Mean HCT ± (SD) | 34.3 (3.25) | 32.04 (5.6) | 41.5 (36.2,46.8) | 0.03 |
 Mean MCV ± (SD) | 89.04 (7.0) | 86.00 (8.14) | 89.5 (77.7–97.9) | 0.014 |
 Median MCH (IQR) | 29.0 (26.7,30.6) | 27.7 (24.9,29.6) | 29.3 (24.2,33.1) | 0.014 |
 Median RDW (IQR) | 16.45 (15.43,18.0) | 18.1 (16.05,21.2) |  | < 0.001 |
White blood cell counts | ||||
 Median WBC count (IQR) | 8.4 (7.0,10.3) | 12.1 (8.9,15.05) | 4.8 (3.2,8.0) | < 0.001 |
 Median Neutrophil count (IQR) | 5.6 (4.65,7.38) | 9.7 (6.22,12.3) | 2.3 (1.2,5.4) | < 0.001 |
 Median Basophil (IQR) | 0.04 (0.03,0.06) | 0.04 (0.03,0.06) |  | 0.924 |
 Median Eosinophil count (IQR) | 0.10 (0.5,0.2) | 0.01 (0.003,0.05) |  | < 0.001 |
 Median monocytes count (IQR) | 0.55 (0.4,0.67) | 0.53 (0.28,0.76) |  | 0.462 |
 Mean lymphocytes ± (SD) | 1.90 (0.54) | 1.73 (0.73) | 1.9 (1.1,3.1) | 0.124 |
Platelets counts and coagulation | ||||
 Median Platelets count (IQR) | 232.5 (204,269) | 196 (143,240) | 271 (151,425) | < 0.001 |
 Median PTT (IQR) | 25.7 (24.6,26.6) | 26.(24.5,27.5) |  | 0.38 |
 Median PT (IQR) | 9.3 (9.1,9.8) | 8.7 (8.2,9.5) |  | < 0.001 |
 Median INR (IQR) | 0.88 (0.85,0.92) | 0.82 (0.78,0.88) |  | < 0.001 |
Cytokines | ||||
 Median interleukin 6 (IQR) | 5.22 (4.8,6.3) | 12.05 (6.31,23.91) |  | < 0.001 |
 Median interleukin 10 (IQR) | 42.4 (38.1,46.7) | 46.7 (42.4,58.7) |  | < 0.001 |
 Median TNF – α (IQR) | 19.8 (17.5,23.4) | 21.7 (17.9,26.1) |  | 0.127 |