Downregulation of α7 nicotinic acetylcholine receptors in peripheral blood monocytes is associated with enhanced inflammation in preeclampsia

Table 1 Characteristics of nonpregnant, normotensive pregnant, and preeclamptic women

Variable	Nonpregnant (n = 30)	Normotensive (n = 32)	Preeclamptic (n = 35)
Age, years	27.3 ± 4.3	26.3 ± 2.8	26.7 ± 5.1
Gestational age (weeks)	N/A	35.5 ± 1.6	35.1 ± 1.5
Parity	N/A	0.22 ± 0.42	0.20 ± 0.41
Systolic BP (mmHg)	107.6 ± 5.3	108.8 ± 7.1	157.1 ± 7.6**
Diastolic BP (mmHg)	67.5 ± 4.5	68.2 ± 5.5	107.6 ± 7.1**
Proteinuria (g/24 h)	< 0.3	< 0.3	2.6 ± 0.5
Uric acid (mg/dL)	3.6 ± 0.6	3.9 ± 0.7	6.2 ± 0.6**

Data are mean ± standard deviation. BP blood pressure. Data were analyzed using one-way ANOVA followed by Bonferroni post-test. **p < 0.01 vs. nonpregnant and normotensive pregnant groups. Proteinuria of all patients from the nonpregnant and normotensive groups was below the detection limit of the measurement

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