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Table 2 Subsequent pregnancies and their outcomes in women with a history of PAS

From: Pregnancy-associated stroke –a systematic review of subsequent pregnancies and maternal health

Author

PAS women (n)

CVT (n)

IS (n)

NS (n)

Women with subsequent pregnancies (n)

Pregnancies (n)

Miscarriage (n)

Induced abortion (n)

Live births (n)

Fetal death (n)

Pregnancy > w22 complications raported (n)

Uncomplicated pregnancies (n)

PROM (n)

Pre-eclampsia (n)

Stroke recurrence(n)

Underlying disease

Appenzeller et al. [24]

6

6

0

0

2

2

nr

nr

2

0

2

2

0

0

0

none

Lamy et al. [20]

37

9

28

0

15

24

nr

nr

11

0

nr

nr

nr

nr

nr

2 CVT patients: hematologic disease

Crovetto et al. [25]

1

0

1

0

1

1

0

0

1

0

1

1

0

0

0

Antiphospholipid syndrome

Coppage et al. [21]

4

1

1

2

4

9

3

0

5

1

6

1

3

1

0

1 patient PSD; 1 patient PCD; 2 patients uncontrolled hyprtension

Ciron et al.* [27]

6

6

0

0

nr

2

1

1

0

0

0

0

0

0

1

1 patient: sickle cell disease

Mehraein et al. [29]

4

4

0

0

4

6

1

0

5

0

5

5

0

0

0

nr

Ferro et al. ** [23]

77

77

0

0

nr

11

1

2

8

0

8

8

0

0

0

nr

Total

135

103

30

2

26

55

6

3

32

1

22

17

3

1

1

 
  1. CVT Cerebral vein thrombosis, IS Ischemic stroke, NS stroke type not specified, PROM premature rupture of membranes, PSD Protein S deficiency, PCD Protein C deficiency, nr not reported for women with PAS. *Ciron et al. reported that in 9.7% (n = 6) of 62 women with CVT in reproductive age it was related to pregnancy. The authors report the number of pregnancies and their outcomes for one women with a PAS history, but do not state whether the other women with PAS history had pregnancies. **Ferro et al. reported that there were 8 uncomplicated pregnancies, 1 miscarriage and 2 induced abortions, but do not state amongst how many women these pregnancies occurred