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Table 4 The risk of preeclampsia by stage 1 hypertension in early gestation and changes in systolic and diastolic blood pressure from early to mid-gestation

From: Elevated diastolic blood pressure until mid-gestation is associated with preeclampsia and small-for-gestational-age birth: a population-based register study

cBP changes until mid-gestation Preeclampsia total
Early gestation blood pressured
Normal (<  130/80 mmHg)
n = 56,491
Stage 1 hypertensione
n = 7996
% Adjusted OR (95% CI)f % Adjusted OR (95% CI)f
Systolic BPc
 Lowereda 2.8 1.0 6.5 1.9 (1.7–2.2)
 Elevatedb 3.2 1.1 (1.0–1.2) 9.0 2.8 (2.3–3.4)
Diastolic BPc
 Lowereda 2.6 1.0 6.6 2.2 (1.9–2.5)
 Elevatedb 3.9 1.4 (1.3–1.6) 9.9 3.4 (2.6–4.4)
  1. cBP Blood pressure. The changes in systolic and diastolic BP from early to mid-gestation were categorized in the following groups; a) lowered BP, defined as no change or decrease by 1 mmHg or more and b) elevated BP, defined as an increase by 1 mmHg or more between early to mid-gestation. dBlood pressure before 16 weeks. eStage 1 hypertension: Systolic BP 130–139 mmHg or diastolic BP 80–89 mmHg.fAdjusted OR (95% CI): Odds ratios with 95% confidence intervals, adjusted for maternal body mass index, smoking, age, recurrent miscarriages before the index pregnancy and country of birth