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Table 1 Characteristics of the study participants

From: Use of antidepressants and anxiolytics in early pregnancy and the risk of preeclampsia and gestational hypertension: a prospective study

 

Women without HDP n = 6444

PE women n = 122

GH women n = 195

Maternal age at deliverya (years)

29.96 ± 4.32

30.00 ± 4.68

29.90 ± 4.27

% Para 0

46.21%

68.85%†

67.69%†

% Smokers during pregnancy

13.09%

7.9%

8.15%‡

% 2 Caucasian parents

96.95%

93.91%

98.32%

Pre-pregnancy BMI (kg/m2)a

24.10 ± 5.13

27.61 ± 6.75†

27.34 ± 6.38†

% Pre-pregnancy hypertension

1.10%

11.67%†

9.28%†

MAP at the first visit (mmHg)

83.07 ± 7.86

89.10 ± 9.21†

91.27 ± 9.42†

Gestational age at deliverya (wk)

39.44 ± 1.52

37.79 ± 2.09†

39.15 ± 1.38†

% GDM

6.78%

14.75%‡

13.84%‡

% Past history of HDP

3.80%

14.88%‡

18.84%†

% antidepressant and/or anxiolytic users during the first trimester

3.07% (n = 198)

9.02%‡ (n = 11)

4.62% (n = 9)

% Non-medicated depression or anxiety

0.59% (n = 38)

1.64% (n = 2)

0.51% (n = 1)

  1. amean ± SD
  2. compared to women without HDP: †p < 0,001; ‡p < 0,05
  3. BMI body mass index, GDM gestational diabetes mellitus, GH gestational hypertension, HDP hypertensive disorders of pregnancy, MAP mean arterial pressure, PE preeclampsia