Natural conception | OI without ART | Conventional IVT-ET | ICSI | |||||
---|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | N | % | |
All women and a fetus/neonate born ≥22 weeks | ||||||||
Maternal outcomes | N = 90,506 | N = 3939 | N = 1476 | N = 1671 | ||||
Placenta previa | 489 | 0.5 | 22 | 0.6 | 36 | 2.4 | 30 | 1.8 |
Placental abruption | 382 | 0.4 | 19 | 0.5 | 8 | 0.5 | 19 | 1.2 |
MAP | 172 | 0.2 | 9 | 0.2 | 17 | 1.2 | 24 | 1.5 |
Gestational diabetes | 2304 | 2.6 | 138 | 3.5 | 76 | 5.2 | 80 | 4.8 |
PIH | 2632 | 2.9 | 177 | 4.5 | 101 | 6.9 | 107 | 6.5 |
Cesarean section | 16,433 | 18.5 | 933 | 24.2 | 563 | 38.6 | 617 | 37.8 |
Blood transfusion | 377 | 0.4 | 20 | 0.5 | 36 | 2.4 | 38 | 2.3 |
ICU admission | 105 | 0.1 | 8 | 0.2 | 7 | 0.5 | 15 | 0.9 |
Maternal death | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fetal/neonatal outcomes | N = 89,576 | N = 4067 | N = 1518 | N = 1699 | ||||
Stillbirth | 230 | 0.3 | 17 | 0.4 | 10 | 0.7 | 5 | 0.3 |
Preterm birth < 37 w | 4768 | 5.3 | 423 | 10.4 | 184 | 12.1 | 181 | 10.7 |
Low birth weight < 2500 g | 7980 | 8.9 | 651 | 16.0 | 243 | 16.0 | 245 | 14.4 |
Women with a singleton pregnancy and singleton born ≥22 weeks | ||||||||
Maternal outcomes | N = 88,873 | N = 3702 | N = 1407 | N = 1586 | ||||
Placenta previa | 486 | 0.5 | 20 | 0.5 | 34 | 2.4 | 28 | 1.8 |
Placental abruption | 380 | 0.4 | 18 | 0.5 | 8 | 0.6 | 19 | 1.2 |
MAP | 172 | 0.2 | 8 | 0.2 | 17 | 1.2 | 24 | 1.5 |
Gestational diabetes | 2271 | 2.6 | 132 | 3.6 | 72 | 5.1 | 75 | 4.7 |
PIH | 2573 | 2.9 | 165 | 4.5 | 93 | 6.6 | 102 | 6.4 |
Cesarean section | 15,912 | 18.0 | 780 | 21.2 | 509 | 36.5 | 558 | 35.6 |
Blood transfusion | 368 | 0.4 | 16 | 0.4 | 33 | 2.4 | 37 | 2.3 |
ICU admission | 97 | 0.1 | 5 | 0.1 | 7 | 0.5 | 12 | 0.8 |
Maternal death | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fetal/neonatal outcomes | N = 88,337 | N = 3682 | N = 1393 | N = 1570 | ||||
Stillbirth | 216 | 0.2 | 8 | 0.2 | 8 | 0.6 | 4 | 0.3 |
Preterm birth | 4153 | 4.7 | 211 | 5.7 | 120 | 8.6 | 119 | 7.6 |
Low birth weight < 2500 g | 7141 | 8.1 | 373 | 10.1 | 159 | 11.4 | 159 | 10.1 |
Women with multiple pregnancies and multiples born ≥22 weeks | ||||||||
Maternal outcomes | N = 625 | N = 189 | N = 63 | N = 66 | ||||
Placenta previa | 3 | 0.5 | 1 | 0.5 | 2 | 3.2 | 2 | 3.1 |
Placental abruption | 2 | 0.3 | 1 | 0.5 | 0 | 0 | 0 | 0 |
MAP | 0 | 0 | 1 | 0.5 | 0 | 0 | 0 | 0 |
Gestational diabetes | 31 | 5.1 | 6 | 3.2 | 4 | 6.3 | 5 | 7.8 |
PIH | 57 | 9.4 | 12 | 6.5 | 8 | 12.7 | 5 | 7.8 |
Cesarean section | 518 | 85.8 | 151 | 81.2 | 54 | 87.1 | 59 | 92.2 |
Blood transfusion | 9 | 1.5 | 3 | 1.6 | 3 | 4.8 | 1 | 1.6 |
ICU admission | 8 | 1.3 | 3 | 1.6 | 0 | 0 | 3 | 4.7 |
Maternal death | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fetal/neonatal outcomes | N = 1209 | N = 383 | N = 125 | N = 129 | ||||
Stillbirth | 13 | 1.1 | 9 | 2.3 | 2 | 1.6 | 1 | 0.8 |
Preterm birth | 613 | 50.7 | 212 | 55.4 | 64 | 51.2 | 62 | 48.1 |
Low birth weight < 2500 g | 838 | 69.3 | 278 | 72.8 | 84 | 67.2 | 86 | 66.7 |