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Table 4 Prevalence of common chromosome abnormalities [trisomies (T) 21, 18 and 13 and sex chromosome abnormalities] and atypical (or other) abnormalities in screen-positive pregnancies with or without any of the four risk factors, including a risk of T21 > 1 in 100,a nuchal translucency (NT) ≥ 3.5 mm, a low pregnancy associated plasma protein A (PAPP-A) < 0.2 multiple of medians, and a high risk for both trisomy 21 and trisomy 18

From: Factors associated with common and atypical chromosome abnormalities after positive combined first-trimester screening in Chinese women: a retrospective cohort study

 

Common abnormalities

Atypical abnormalities

No risk factors

1.1%

0.6%

One or more of the risk factors

11.5%

1.7%