Table 3 Hematological parameters at different time points in the study
Parameter | FCM (n = 50) | ISC (n = 50) | Differences in mean between study groups (95% confidence interval) | P value |
|---|---|---|---|---|
Hemoglobin(g/L) | ||||
Baseline | 85.7 ± 8.9 | 86.7 ± 8.6 | 1(−4.49,2.49) | 0.57 |
3 weeks | 10 6 ± 12.1 | 100.1 ± 7.2 | 6(2.0, 9.8) | 0.003 |
6 weeks | 114.8 ± 6.9 | 108.2 ± 6.8 | 7(3.9,9.3) | < 0.001 |
12 weeks | 115.3 ± 4.6 | 108.8 ± 4.4 | 6.5 (4.7,8.29) | < 0.001 |
Mean corpuscular volume (fL) | ||||
Baseline | 75.5 ± 6.0 | 75.3 ± 5.3 | 0.2 (−1.93,2.46) | 0.82 |
3 weeks | 82.2 ± 5.5 | 81.4 ± 4.4 | 0.8 (− 1.20, 2.70) | 0.45 |
6 weeks | 86.4 ± 3.4 | 86.2 ± 4.2 | 0.2 (− 1.26, 1.73) | 0.76 |
12 weeks | 88.9 ± 2.1 | 88.2 ± 2.4 | 0.7 (− 0.25, 1.50) | 0.16 |
Mean corpuscular hemoglobin (pg) | ||||
Baseline | 24.4 ± 2.7 | 24.4 ± 2.2 | −0.03 (− 0.99, 0.93) | 0.94 |
3 weeks | 27.5 ± 1.6 | 27.4 ± 1.7 | 0.07 (− 0.56, 0.71) | 0.82 |
6 weeks | 29.0 ± 1.4 | 28.8 ± 1.3 | 0.24 (− 0.28, 0.76) | 0.37 |
12 weeks | 30.4 ± 1.4 | 29.8 ± 1.4 | 0.6 (0.001, 1.1) | 0.049 |
Mean corpuscular hemoglobin concentration (g/dL) | ||||
Baseline | 29.7 ± 1.9 | 30.0 ± 1.8 | −0.30 (−1.005, 0.41) | 0.41 |
3 weeks | 31.7 ± 1.8 | 31.8 ± 1.5 | − 0.05 (− 0.69,0.59) | 0.88 |
6 weeks | 32.9 ± 1.5 | 33.1 ± 1.1 | −0.26 (− 0.78, 0.25) | 0.31 |
12 weeks | 33.7 ± 0.9 | 33.7 ± 0.9 | −0.002 (− 0.36, 0.35) | 0.99 |
Red cell distribution width (%) | ||||
Baseline | 21.9 ± 6.04 | 20.5 ± 5.49 | 1.4 (−0.89, 3.61) | 0.24 |
3 weeks | 20.7 ± 5.34 | 20.0 ± 4.09 | 0.7 (− 1.17, 2.54) | 0.47 |
6 weeks | 16.2 ± 3.19 | 15.8 ± 2.89 | 0.4 (− 0.85, 1.53) | 0.58 |
12 weeks | 13.6 ± 1.51 | 13.5 ± 1.38 | 0.1 (− 0.45, 0.68) | 0.68 |