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Table 3 Extent to which test characteristics affect decision vs preferred screening and diagnostic technology (numbers are averages of scores on 1–5 Likert scales, with 1 – disagreement, 5 – agreement)

From: The value of non-invasive prenatal testing: preferences of Canadian pregnant women, their partners, and health professionals regarding NIPT use and access

Test characteristics Women choosing NIPT Women choosing current screening % of all women for whom this test characteristic ‘strongly influenced’ their decision p-value comparing the 2 groups
NIPT is much more accurate than current screening in assessing the risk of DS 4.64 3.11 64.5% < 0.001
Results of NIPT can be available earlier in the pregnancy than the result of current screening 4.57 2.94 62.9% < 0.001
Current screening estimates the risk that the baby has neural tube defects and NIPT doesn’t 2.55 4.11 15.9% < 0.001
Current screening can indicate the possibility of pregnancy and labor complications and NIPT cannot 2.40 3.98 13.4% < 0.001
   Women choosing amniocentesis   
With NIPT there is no increased risk of miscarriage 4.78 2.93 66.5% < 0.001
NIPT is more convenient than amniocentesis (only requires a blood draw) 4.24 2.61 46.9% < 0.001
NIPT tests for the common chromosome disorders (like Down Syndrome), which is all I need to know 3.89 2.43 28.5% < 0.001
Amniocentesis is more accurate than NIPT 2.46 4.61 24.2% < 0.001
Amniocentesis gives more information about possible chromosome anomalies than NIPT 2.53 4.57 21.9% < 0.001