Screening of differentially expressed proteins from syncytiotrophoblast for severe early-onset preeclampsia in women with gestational diabetes mellitus using tandem mass tag quantitative proteomics

Table 2 The differentially expressed proteins identified in syncytiotrophoblast from patients with GDM with subsequently developed PE and patients with GDM

Protein name	Accession No	Gene name	Fold change	P value
WD repeat-containing protein 1	O75083	WDR1	1.600	0.026
Vascular endothelial growth factor receptor 1	P17948	FLT1	1.377	0.031
15-hydroxyprostaglandin dehydrogenase	P15428	HPGD	1.366	0.015
Ribonuclease H2, subunit C	E9PKP0	RNASEH2C	1.339	0.001
Amine oxidase	D3DX03	ABP1	1.311	0.003
cDNA FLJ51917	B4DNZ4	N/A	1.261	0.040
Mucin 1	B6ECB2	MUC1	1.256	0.049
Annexin A4	P09525	ANXA4	1.251	0.049
cDNA FLJ38330	Q8N959	N/A	1.235	0.045
Pappalysin-2	Q9BXP8	PAPPA2	1.221	0.015
ERO1-like protein 1 alpha	Q96HE7	ERO1A	1.205	0.011
KIF 1-binding protein	Q96EK5	KIF1BP	0.826	0.047
Activating transcription factor 3	Q7Z567	ATF3	0.823	0.041
Thioredoxin reductase 1	E9PIR7	TXNRD1	0.822	0.027
cDNA FLJ16285	B3KV96	N/A	0.815	0.035
NADH dehydrogenase flavoprotein 3	P56181	NDUFV3	0.815	0.010
Glutathione S-transferase A3	Q5JW85	GSTA3	0.802	0.045
Tether containing UBX domain for GLUT4	J3QL04	ASPSCR1	0.795	0.037
Trichohyalin	Q07283	TCHH	0.789	0.044
Solute carrier family 13	Q59HF0	N/A	0.781	0.009
MRG/MORF4L-binding protein	Q9NV56	MRGBP	0.776	0.042
Adenosylhomocysteinase 2	Q96HN2	AHCYL2	0.746	0.028
Polyadenylate-binding protein 4	B1ANR0	PABPC4	0.744	0.025

ISSN: 1471-2393