Skip to main content

Table 5 Summary of studies – guidelines or information for providers

From: Adjunct clinical interventions that influence vaginal birth after cesarean rates: systematic review

Study;

Design;

Country, setting;

Funding

Population;

Study period

Intervention & comparator (no. of participants)

TOLAC ratea

VBAC ratea

VBAC/TOLAC ratea

Bellows (2016)

Non-concurrent cohort

US, tertiary care academic hospital

Funding NR

All women who underwent TOLAC, at least one prior CD & live, singleton gestation in cephalic presentation, 24 0/7 weeks of gestation

July 1, 2009-December 31, 2013

Grp 1 (2009–2011): pre-2011 guideline (n = 450)

Grp 2 (2011–2013): post-2011 guideline implementation (offering TOLAC; inducing labor; administering oxytocin) (n = 781)

NR

Grp 1: NR (26.0%)

Grp 2: NR (33.3%)

Grp 1: 351 (78.1%)

Grp 2: 616 (78.9%), p = 0.75

Kosecoff (1987)

Retrospective cohort

US, acute, non-specialty, nonfederal hospitals > 150 beds.

Non-industry funded

Women with previous low transverse CS

January 1979–December 1979 (time 1)

January 1980–September 1980 (time 2)

July 1981–June 1982 (time 3)

Period 1 (January–December 1979) & Period 2 (January–September 1980): before NIH Consensus Development conference recommendations (n = 35 & n = 64)

Period 3 (1981–1982): after conference recommendations; women should be given TOLAC for potential VD (n = 70)

Period 1: 2 (5.7%)

Period 2: 7 (10.9%)

vs.

Period 3: 20 (28.6%)

Period 1: 2 (5.7%)

Period 2: 4 (6.3%)

vs.

Period 3: 11 (15.7%)

Period 1: 2 (100%)

Period 2: 4 (57.1%)

vs.

Period 3: 11 (55.0%)

Pinette (2004)

Non-concurrent cohort

US, birth certificate & hospital reported data

Funding NR

All women with previous CS giving birth at 20 weeks of gestation or more

1998–2001

Grp 1 (1998): pre-exposure (birth certificate n = 1410; hospital data n = 1386)

Grp 2 (1999–2001): ACOG guideline revision (birth certificate data n = 4463; hospital data n = 4015)

NR

Birth certificate data:

1998: 424 (30.1%)

vs.

1999: 327 (22.6%)

2000: 277 (17.9%)

2001: 193 (13.1%)

1988 vs. 2001,

RR 2.8 (95% CI 2.5–3.2), p < 0.01

Hospital-reported data:

1998: 489 (35.3%)

vs.

1999: 411 (28.2%)

2000: 321 (23.1%)

2001: 156 (13.3%)

RR 3.5 (95% CI 3.1–4.2), p < 0.01

NR

Sanchez –Ramos (1990)

Non-concurrent cohort

US, regional perinatal center

Funding NR

Women with one or two previous CS, with low transverse or vertical scars not extending into uterine corpus

1986–1989

Grp 1 (1986–1987): before July 1, 1987 department-wide guideline change (n = 899)

Grp 2 (1988–1989): after July 1, 1987, new guidelines for intrapartum management (n = 1105)

1986: 139 (31.7%)

1987: 193 (41.9%)

vs.

1988: 402 (76.6%)

1989: 487 (84.0%);

Difference: 52.2%, p < 0.0001

1986: 90 (20.5%)

1987: 142 (30.8%)

vs.

1988: 342 (65.1%)

1989: 403 (69.5%);

Difference: 48.9%; p < 0.0001

1986: 90 (64.7%)

1987: 142 (73.6%)

vs.

1988: 342 (85.1%)

1989: 403 (82.8%);

Difference: 18.0%; p < 0.0001

Santerre (1996)

Non-concurrent cohort

US, hospitals

Funding NR

Women with a previous CS

1987–1991

Grp 1 (before 1987–1988): before practice guideline implementation (n = NR)

Grp 2 (after Oct. 1988): ACOG practice guideline, prior cesarean section no longer a reason for repeat cesarean (n = NR)

NR

VBAC rate in US (data for Massachusetts hospitals NR)

1985: 6.6%

1986: 8.5%

1987: 9.8%

1988: 12.6%

vs.

1989: 18.5%

1990: 20.4%

1991: 24.2%

1992: 25.1%

1993: 25.4%

NR

Studnicki (1997)

Non-concurrent cohort

US, nonfederal acute care provider hospitals

Funding NR

Women with prior CS

1990–1993

Grp 1 (1990–1992): before practice guidelines

(n = 66,702)

Grp 2 (1993): after legislatively imposed practice guidelines (n = 23,142)

NR

1990: 4816 (21.8%)

1991: 5540 (25.6%)

1992: 6133 (26.7%)

vs.

1993: 7151 (30.9%)

NR

Zweifler (2006)

Non-concurrent cohort

US, California Department of Health Services Birth Statistical Master Files

Funding NR

Women who previously gave birth by cesarean delivery & had singleton birth planned in a California hospital

1996–2002

Grp 1 (1996–1999): before ACOG VBAC guideline revision (n = NRb)

Grp 2 (2000–2002): after ACOG VBAC guideline revision (n = NRb)

Attempted VBAC:

Grp 1: NR (24.0%)

Grp 2: NR (13.5%)

Difference: 44% decrease, p < 0.001

1996–2002: 61,684 (16.0%)

NR

  1. no. number, TOLAC trial of labor after cesarean, VBAC vaginal birth after cesarean, US United States, NR not reported, CD cesarean delivery, Grp group, CS cesarean section, NIH National Institute of Health, VD vaginal delivery, vs. versus, ACOG American College of Obstetricians and Gynecologists, RR relative risk, CI confidence interval
  2. aResults of statistical tests or summary statistics were extracted whenever these were reported within studies
  3. bStudy reported number of live births separately from number of women; table reflects data for number of women whenever this was reported