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Table 7 Summary of observations based on haemodynamic effects of oxytocin administered at first injection T1-T2 (Table 4) and second injection T2-T3 (Tables 5 and 6). For further explanation of comparisons, see Fig. 1, and for explanation of interpretations, see text

From: Effects of oxytocin and anaesthesia on vascular tone in pregnant women: a randomised double-blind placebo-controlled study using non-invasive pulse wave analysis

Variable

Table 4

T1-T2 in OP group

N = 24

Table 5

T2-T3 in PO group

N = 26

Table 6

T1-T2 vs. T2-T3 in PO group

N = 26

Summary of observations

MAP (mmHg)

No changea

Decrease

Decrease

Decrease

HR (bpm)

Increase

Increase

Increase

Increase

ECG ST index

No change

Decrease

Decrease

Decrease

PH

No changeb

Increase ➔ peripheral vasodilation

Increase ➔peripheral vasodilation

Increase ➔ peripheral vasodilation

ETc (ms)

Increase ➔ large-artery vasodilation, decreased afterload, decreased SVR, increased preload

No change

No change

Increase ➔ large-artery vasodilation, decreased afterload, decreased SVR, increased preload

EEI

No change

No change

N/Ac

No change

EEI@75

No change

No change

N/Ac

No change

DI

Decrease ➔ small-artery vasodilation

Decrease ➔ small-artery vasodilation

Decrease ➔ small-artery vasodilation

Decrease ➔ small artery vasodilation

DI@75

Decrease ➔ small-artery vasodilation

Decrease ➔ small-artery vasodilation

No change

Decrease ➔ small artery vasodilation

b/a

No change

No change

No change/decrease ➔ large-artery vasodilation,

increase in LV ejection

No change

d/a

No change

No change

No change

No change

AI

No change

No change

No change

No change

  1. a) MAP increased after both oxytocin and placebo
  2. b) PH increased after both oxytocin and placebo, indicating peripheral vasodilation
  3. c) EEI and EEI@75 statistics could not be performed due to too few cases in comparisons (N = 10)