Table 6 Haemodynamic effects of oxytocin (administered during sequence T2-T3) relative to placebo (sequence T1-T2) in first trimester pregnant women in the placebo-oxytocin group (N = 26). For interpretation and comparisons of oxytocin effects, see Table 7
Variable | Placebo Δ value T1-T2a Mean ± SD Median (range) | Oxytocin Δ value T2-T3b Mean ± SD Median (range) | Significance of differencec (P) |
|---|---|---|---|
MAP (mmHg) | 10 ± 9 10 (− 13, 23) | − 3 ± 7 − 2 (− 16, 12) | 0.0002 |
HR (bpm) | 0 ± 5 0 (− 13, 9) | 6 ± 7 4 (− 4, 22) | 0.020 |
ECG ST index | 0.14 ± 0.16 0.10 (− 0.10, 0.50) | − 0.15 ± 0.28 − 0.10 (− 0.90, 0.30) | 0.001 |
PH | 4.7 ± 2.9 4.1 (− 0.8, 10.1) | 1.0 ± 1.8 0.9 (− 2.8, 3.4) | 0.005 |
ETc (ms) | −3 ± 48 5 (− 200, 55) | 2 ± 48 6 (− 160, 107) | 0.70 |
DI | 0.00 ± 0.18 − 0.02 (− 0.41, 0.46) | − 0.11 ± 0.16 − 0.14 (− 0.34, 0.30) | 0.016 |
DI@75 | 0.00 ± 0.18 0.00 (− 0.39, 0.49) | −0.06 ± 0.17 − 0.01 (− 0.25, 0.50) | 0.11 |
b/a | 0.06 ± 0.15 0.02 (− 0.19, 0.53) | −0.02 ± 0.08 − 0.05 (− 0.14, 0.21) | 0.024 |
d/a | −0.04 ± 0.13 − 0.03 (− 0.39, 0.27) | −0.02 ± 0.09 − 0.00 (− 0.18, 0.16) | 0.78 |
AI | 0.07 ± 0.23 0.08 (− 0.55, 0.62) | 0.06 ± 0.20 0.04 (− 0.26. 0.47) | 0.94 |