Patients | n = 1038 |
---|---|
Maternal characteristics | |
Age (years) | 31.0 (28.0–35.0)a |
BMI (kg/m2) | 23.2 (21.0–26.3) |
Ethnicity Caucasian | 747 (72%)b |
Nulliparity | 534 (51%) |
Gestational age | 39.7 (38.1–40.7) |
Mode of birth | |
Caesarean section | 254 (24%) |
Vaginal | 780 (75%) |
Comorbidity | |
Pre-eclampsia/ HELLP | 104 (10%) |
Anti-coagulant use | 6 (0.6%) |
Transfer to hospital | |
No transfer (birth in hospital) | 753 (73%) |
Transfer to hospital during labour | 157 (15%) |
Postpartum transfer (birth at home) | 128 (12%) |
Primary cause of bleeding | |
Uterine atony | 684 (66%) |
Retained placenta | 168 (16%) |
Pathological ingrowth of placenta | 89 (9%) |
Surgical bleeding and abruption/coagulopathy | 97(9%) |
Placentation | |
Abnormal localisation placenta | 65 (6%) |
Pathological ingrowth placenta | 97 (9%) |
Composite endpoint severe maternal morbidity and mortality | 355 (34%) |
Embolisation | 124 (12%) |
Hysterectomy | 57 (5%) |
Emergency B-Lynch | 27 (3%) |
Ligation arteries | 7 (0.7%) |
ICU admission | 295 (28%) |
Maternal mortality | 6 (0.6%) |
Haemostatic interventions | |
Fibrinogen administered | 98 (9%) |
Tranexamic acid administered | 473 (46%) |
Recombinant FVIIa administered | 29 (3%) |
Bleeding characteristics | |
Bleeding rate (ml/min) c | 2.4 (1.3–4.8) |
Shock | 927 (89%) |
Total volume blood loss (L) | 3.0 (2.5–4.0) |
Total volume of clear fluids (L) | 3.0 (2.0–4.0) |
Total units of blood products (n) | 6.0 (4.0–8.0) |