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Table 4 Diagnostic performance of sFlt-1:PlGF ratio ≥ 38 for preeclampsia, and < 10th and < 3rd centile infants

From: Assessing the sensitivity of placental growth factor and soluble fms-like tyrosine kinase 1 at 36 weeks’ gestation to predict small-for-gestational-age infants or late-onset preeclampsia: a prospective nested case-control study

Outcome Sensitivity Specificity PPV NPV
Preeclampsia 66.7%
[49.8–80.9%]
94.2%
[90.1–97.0%]
31.8%
[20.5–45.8%]
98.6%
[97.8–99.1%]
Birthweight < 10th centile (All SGA) 24.5%
[16.5–34.0%]
94.2%
[90.1–97.0%]
32.4%
[20.1–47.8%]
91.7%
[90.7–92.5%]
Birthweight < 3rd centile (All SGA) 25.0%
[10.7–44.9%]
89.3%
[85.1–92.7%]
6.3%
[3.2–12.3%]
97.6%
[97.1–98.1%]
  1. Data presented with [95% Confidence Interval]. NPV Negative Predictive value, PlGF placental growth factor, PPV Positive Predictive Value, sFlt-1 soluble fms-like tyrosine kinase-1, SGA small-for-gestational-age