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Table 1 Participant characteristics compared between controls and: (i) those with a SGA infant; (ii) women who developed preeclampsia

From: Assessing the sensitivity of placental growth factor and soluble fms-like tyrosine kinase 1 at 36 weeks’ gestation to predict small-for-gestational-age infants or late-onset preeclampsia: a prospective nested case-control study

 

Controls (n = 207)

All SGA (n = 102)

P

Preeclampsia (n = 39)

P

Age (years)

32.1 (4.7)

31.9 (4.2)

0.72

33.1 (4.7)

0.27

Booking Body Mass Index (kg/m2)

25.4 (4.6)

25.4 (5.8)

0.45

27.6 (6.0)

0.02

Smoking status

 Current smoker

17 (8.2%)

8 (7.8%)

0.98

2 (5.1%)

0.80

 Ex-smoker

51 (24.6%)

26 (25.5%)

 

10 (25.6%)

 

 Never

139 (67.1%)

68 (66.7%)

 

27 (69.2%)

 

Gestational diabetes mellitus

38 (18.4%)

18 (17.6%)

1.00

9 (23.1%)

0.51

Parity

 0

118 (57.0%)

58 (56.9%)

0.97

28 (71.8%)

0.20

 1

65 (31.4%)

33 (32.4%)

 

9 (23.1%)

 

  > 1

24 (11.6%)

11 (10.8%)

 

2 (5.1%)

 

Onset of delivery

 Induction of labour

88 (42.5%)

47 (46.1%)

0.08

19 (48.7%)

0.25

 Spontaneous labour

96 (46.4%)

36 (35.3%)

 

13 (33.3%)

 

 No labour

23 (11.1%)

19 (18.6%)

 

7 (17.9%)

 

Mode of delivery

 Normal vaginal delivery

102 (49.3%)

45 (44.1%)

0.64

11 (28.2%)

0.01

 Instrumental delivery

42 (20.3%)

22 (21.6%)

 

7 (17.9%)

 

 Emergency caesarean

42 (20.3%)

20 (19.6%)

 

17 (43.6%)

 

 Elective caesarean

21 (10.1%)

15 (14.7%)

 

4 (10.3%)

 

Birthweight (g)

3547 (444)

2683 (333)

< 0.0001

3308 (640)

0.005

Birthweight centile

52.1 (26.1)

5.3 (3.0)

< 0.0001

42.8 (30.4)

0.049

Gestational age at delivery (weeks+days)

39+ 5 (1+ 1)

39+ 0 (1+ 4)

< 0.0001

39+ 0 (1+ 4)

0.03

  1. Data represented as mean (standard deviation), or number (%). g grams, kg kilograms, m metres, n number, PlGF placental growth factor, sFlt-1 soluble fms-like tyrosine kinase 1, SGA small-for-gestational-age (birthweight <10th centile). Note: some percentages do not sum to 100% due to rounding to one decimal place