Characteristics | Case (n = 634) | Control (n = 864) | P-value | OR | 95% CI |
---|---|---|---|---|---|
Maternal educational level (years) | < 0.0001 |  |  | ||
  ≤ 9 | 37 (5.8) | 161 (18.6) |  | 0.2 | 0.2–0.4 |
 10–12 | 85 (13.4) | 147 (17.0) |  | 0.6 | 0.5–0.8 |
 13–16 | 406 (64.0) | 434 (40.2) |  | ref | ref |
  ≥ 17 | 51 (8.0) | 42 (4.7) |  | 1.3 | 0.8–2.0 |
 Unknown | 55 (8.7) | 80 (9.3) |  | 0.7 | 0.5–1.1 |
Maternal antibiotic use in pregnancy* | Â | 0.002 | Â | Â | |
 No | 589 (92.9) | 834 (96.5) |  | ref | ref |
 Yes | 45 (7.1) | 30 (3.5) |  | 2.1 | 1.3–3.4 |
Maternal age at delivery (years) | 28.5 (3.6) | 27.7 (3.8) | 0.0004 | 1.1 | 1.0–1.1 |
Gestational weeks at birth | 38.8 (1.4) | 38.9 (1.4) | 0.1 | 0.9 | 0.9–1.0 |
Birth weight (g) | 3305.6 (480.9) | 3283.9 (500.4) | 0.1 | 1.0 | 1.0–1.0 |
Delivery modes | Â | Â | 0.02 | Â | Â |
 Vaginal delivery | 237 (37.4) | 376 (43.5) |  | ref | ref |
 Caesarean delivery | 397 (62.6) | 488 (56.5) |  | 1.3 | 1.0–1.6 |
Exclusive breastfeeding within the first 6Â months of life | Â | 0.5 | Â | Â | |
 No | 303 (47.8) | 399 (46.2) |  | ref | ref |
 Yes | 331 (52.2) | 465 (53.8) |  | 0.9 | 0.8–1.2 |
Child age (years) | 5.7 (2.0) | 6.3 (2.2) | < 0.0001 | 0.8 | 0.8–0.9 |
Child gender | Â | Â | 0.002 | Â | Â |
 Female | 252 (39.8) | 414 (47.9) |  | ref | ref |
 Male | 382 (60.2) | 450 (52.1) |  | 1.4 | 1.1–1.7 |
Child ethnicity | 0.7 | Â | Â | ||
 Han | 612 (96.5) | 837 (96.8) |  | ref | ref |
 Other | 16 (2.5) | 22 (2.6) |  | 1.0 | 0.5–1.9 |
 Unknown | 6 (1.0) | 5 (0.6) |  | 1.6 | 0.5–5.4 |
Family history of allergic disorders | < 0.0001 |  |  | ||
 No | 289 (45.6) | 679 (78.6) |  | ref | ref |
 Yes | 334 (52.7) | 173 (20.0) |  | 4.5 | 3.6–5.7 |
 Unknown | 14 (1.7) | 12 (1.4) |  | 2.2 | 0.9–4.9 |