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Table 2 Maternal and neonatal outcomes of both groups

From: Perinatal outcomes in intrahepatic cholestasis of pregnancy with monochorionic diamniotic twin pregnancy

 

Mild ICP group(n,%)

Severe ICP group(n,%)

P

OR

GDM

5(13.5%)

8(38.1%)

0.049

3.938(1.084–14.307)

Pre-eclampsia

2(5.4%)

2(9.5%)

0.615

1.842(0.24–14.138)

Hypothyroidism

2(5.4%)

1(4.8%)

1

0.875(0.075–10.268)

placental abruption

1(2.7%)

0

1

0.632(0.518–0.77)

PPROM

2(5.4%)

0

0.53

0.625(0.51–0.766)

postpartum hemorrhage

2(5.4%)

0

0.53

0.625(0.51–0.766)

meconium stained amniotic fluid

18.9%

42.9%

0.069

3.214(0.975–10.6)

GA at delivery (weeks,± SD)

34.95,1.5

34.7,1.4

0.408

 

GA at delivery< 35 weeks

29.7%

42.9%

0.392

1.773(0.581–5.408)

spontaneous preterm delivery

13(35.1%)

4(19.1%)

0.245

0.434(0.121–1.564)

iatrogenic preterm delivery

20(54.1%)

17(81%)

0.05

3.613(1.018–12.82)

iatrogenic preterm delivery with GA < 35 weeks

4(10.8%)

6(28.6%)

0.089

3.3(0.81–13.445)

Mean birth weight(g,± SD)

2223.4316.8

2177.1396.6

0.628

 

NICU

25(67.6%)

13(61.9%)

0.776

0.78(0.255–2.385)

neonatal asphyxia

5(13.5%)

3(14.3%)

1

1.067(0.228–4.993)

aspiration syndrome

2(5.4%)

1(4.8%)

1

0.875(0.075–10.268)

neonatal respiratory distress syndrome

2(5.4%)

2(9.5%)

0.615

1.842(0.24–14.138)

pneumonia

9(24.3%)

9(42.9%)

0.237

2.333(0.743–7.332)

respiratory failure

4(10.8%)

2(9.5%)

1

0.868(0.145–5.195)

hyperbilirubinemia

2(5.4%)

1(4.8%)

1

0.875(0.075–10.268)

hypoglycemia

3(8.1%)

0

0.547

0.618(0.502–0.761)

ventilator-assisted breathing

3(8.1%)

3(14.3%)

0.657

1.889(0.345–10.332)

tracheal intubation assisted breathing

2(5.4%)

2(9.5%)

0.615

1.842(0.24–14.138)

encephalopathy

3(8.1%)

0

0.547

0.618(0.502–0.761)

still-birth

2(5.4%)

1(4.8%)

1

0.87(0.075–10.268)

adverse composite neonatal outcome

8(67.6%)

13(61.9%)

0.438

0.78(0.255–2.385)