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Table 1 Maternal characteristics according to NVP status

From: Nausea and vomiting during pregnancy associated with lower incidence of preterm births: the Japan Environment and Children’s Study (JECS)

 

Total

No NVP

Mild NVP

Moderate NVP

Severe NVP

P value

n = 96,056

n = 16,596

n = 41,198

n = 27,744

n = 10,518

n

n (%)

n (%)

n (%)

n (%)

Maternal Age (years)

  < 20

814

190 (1.2)

256 (0.6)

256 (0.9)

112 (1.1)

<  0.001

 20–24

8630

1678 (10.1)

3026 (7.4)

2787 (10.1)

1139 (10.8)

 

 25–29

26,528

4487 (27.0)

10,775 (26.2)

8111 (29.2)

3155 (30.0)

 

 30–34

34,075

5432 (32.7)

14,997 (36.4)

9967 (35.9)

3679 (35.0)

 

 35–39

21,622

3861 (23.3)

10,038 (24.4)

5636 (20.3)

2087 (19.8)

 

  ≥ 40

4383

945 (5.7)

2106 (5.1)

986 (3.6)

346 (3.3)

 

 Missinga

4

     

Parity

 Nullipara

37,800

8244 (51.4)

15,404 (38.2)

10,040 (36.9)

4112 (40.1)

<  0.001

 Multipara

56,005

7804 (48.6)

24,875 (61.8)

17,170 (63.1)

6156 (60.0)

 

 Missinga

2251

     

Education (years)

  ≤ 12

34,790

6398 (38.7)

14,118 (34.4)

10,320 (37.3)

3954 (37.8)

<  0.001

  > 12

60,893

10,126 (61.3)

26,931 (65.6)

17,315 (62.7)

6521 (62.3)

 

 Missinga

373

     

BMI (kg/m2)

  < 18.5

15,500

2859 (17.2)

6834 (16.6)

4167 (15.0)

1640 (15.6)

<  0.001

 18.5–24.9

70,221

12,141 (73.2)

30,216 (73.4)

20,351 (73.4)

7513 (71.5)

 

  ≥ 25

10,272

1584 (9.6)

4122 (10.0)

3209 (11.6)

1357 (12.9)

 

 Missinga

63

     

Smoking during pregnancy

 No

90,887

15,325 (93.3)

39,155 (95.8)

26,294 (95.5)

10,113 (97.0)

<  0.001

 Yes

4386

1106 (6.7)

1724 (4.2)

1239 (4.5)

317 (3.0)

 

 Missinga

783

     

Pregnancy Complications

 Threatened abortion

11,428

1695 (10.2)

4885 (11.9)

3451 (12.4)

1397 (13.3)

<  0.001

 Threatened premature labor

18,715

2896 (17.5)

7990 (19.4)

5566 (20.1)

2263 (21.5)

<  0.001

 Premature rupture of membrane

7932

1549 (9.3)

3374 (8.2)

2218 (8.0)

791 (7.5)

<  0.001

 Pregnancy-induced hypertension

2964

622 (3.8)

1189 (2.9)

841 (3.0)

312 (3.0)

<  0.001

  1. Chi-squared test
  2. a Not included in percentage distribution