From: The impact of FSH receptor polymorphism on time-to-pregnancy: a cross-sectional single-centre study
Criteria | FSHR genetic variant | |||||
---|---|---|---|---|---|---|
Asn/Asn | Asn/Ser | Ser/Ser | ||||
n | % or Median (25–75% CI) | n | % or Median (25–75% CI) | n | % or Median (25–75% CI) | |
Participants | 101 | 34.7 | 148 | 50.9 | 42 | 14.4 |
Mean age (years) | 27.4 ± 5.9 | 27.2 ± 5.5 | 27.9 ± 5.0 | |||
Median body mass index (kg/m2) | 21.4 (19.8–24.1) | 22.3 (20.0–24.1) | 21.5 (20.1–23.1) | |||
Median TTP (month) | 1.0 (1.0–4.0)* | 1.0 (1.0–3.8)* | 7.0 (1.0–15.3) | |||
TTP < 12 month | 92 | 91.1* | 133 | 89.9* | 27 | 64.3 |
TTP ≥ 12 month | 9 | 8.9 | 15 | 10.1 | 15 | 35.7 |
Nuliparous | 48 | 47.5 | 75 | 50.7 | 25 | 59.5 |
Multiparous | 53 | 52.5 | 73 | 49.3 | 17 | 40.5 |
Living in the city | 76 | 75.3 | 115 | 77.7 | 35 | 83.3 |
Living in the country | 25 | 24.7 | 33 | 22.3 | 7 | 16.7 |
Education lower than college | 37 | 36.6 | 63 | 42.6 | 14 | 33.3 |
College education and higher | 64 | 63.4 | 85 | 57.4 | 28 | 66.7 |
Salary < 560 Euro/month | 34 | 33.7 | 36 | 24.3 | 11 | 26.2 |
Salary ≥560 Euros/month | 67 | 66.3 | 112 | 75.7 | 31 | 73.8 |
Smoking | 28 | 27.7 | 28 | 18.9 | 6 | 14.3 |
Alcohol consumers | 51 | 50.5 | 74 | 50.0 | 20 | 47.6 |
Coffee consumption | 27 | 26.7* | 37 | 25.0* | 32 | 76.2 |
Folic acid use | 24 | 23.8 | 36 | 24.3 | 11 | 26.2 |
Use of other food additives | 32 | 31.7 | 50 | 33.8 | 14 | 33.3 |
Physical activity/sports | 28 | 27.7 | 48 | 32.4 | 16 | 38.1 |
Prior hormonal contraception use | 26 | 25.7 | 31 | 20.9 | 10 | 23.8 |
Regular menstrual cycle | 68 | 67.3* | 113 | 76.4* | 17 | 40.5 |
Irregular menstrual cycle | 33 | 32.7* | 35 | 23.6* | 25 | 59.5 |
Sexual intercourse one time/week | 18 | 17.8 | 27 | 18.2 | 7 | 16.7 |
Sexual intercourse 2 times and more/week | 83 | 82.2 | 121 | 81.8 | 35 | 83.3 |
Past fertility problems | 8 | 7.9 | 6 | 4.0 | 3 | 7.1 |
Gynaecological diseases in the past | 3 | 3.0 | 4 | 2.7 | 1 | 2.4 |
Working status | 93 | 92.1 | 141 | 95.3 | 39 | 92.9 |
Stress | 60 | 59.4 | 55 | 37.2 | 21 | 50.0 |
Use of pesticides | 2 | 1.9 | 1 | 0.7 | 1 | 2.4 |