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Table 3 Association between previous caesarean delivery and neonatal outcomes in the subsequent pregnancy

From: Association between first caesarean delivery and adverse outcomes in subsequent pregnancy: a retrospective cohort study

Neonatal outcomes

previous SVD(n = 6240)

previous CS(n = 5422)

Crude OR1 (95% CI)

Model 1

Adjusted OR1 (95% CI)

previous nonindicated

CS(n = 1827)

Crude OR2 (95% CI)

Model 2

Adjusted OR2 (95% CI)

N

%

N

%

  

N

%

  

Stillbirths

13

0.2%

11

0.2%

0.97 (0.44–2.18)

0.76 (0.27–2.18)a

4

0.2%

1.05 (0.34–3.23)

0.68 (0.13–3.55)a

Preterm delivery

341

5.5%

343

6.3%

1.17 (1.01–1.36)

1.37 (1.14–1.66)b

119

6.5%

1.21 (0.97–1.50)

1.37 (1.06–1.78)b

LBW

162

2.6%

151

2.8%

1.08 (0.86–1.35)

4.25 (2.73–6.62)c

46

2.5%

0.97 (0.70–1.35)

3.78 (2.07–6.90)c

Macrosomia

466

7.5%

317

5.8%

0.77 (0.66–0.89)

4.79 (3.94–5.83)d

110

6.0%

0.79 (0.64–0.98)

5.04 (3.95–6.44)d

Apgar at 1 min<8

79

1.3%

74

1.4%

1.08 (0.78–1.49)

1.13 (0.77–1.66)

25

1.4%

1.08 (0.69–1.70)

1.18 (0.69–2.01)

Neonatal infection

83

1.3%

46

0.8%

0.64 (0.44–0.91)

0.81 (0.54–1.23)

12

0.7%

0.49 (0.27–0.90)

0.51 (0.26–1.03)

Neonatal death

4

0.1%

4

0.1%

1.15 (0.29–4.60)

2.17 (0.34–13.74)

1

0.1%

0.85 (0.10–7.64)

0.70 (0.02–34.51)

Admission to neonatal unit

366

5.9%

355

6.5%

1.12 (0.97–1.31)

1.39 (1.16–1.65)

117

6.4%

1.10 (0.89–1.36)

1.20 (0.94–1.54)

NRDS

13

0.2%

21

0.4%

1.86 (0.93–3.72)

1.88 (0.83–4.24)

7

0.4%

1.84 (0.73–4.62)

1.49 (0.48–4.61)

TTN

71

1.1%

91

1.7%

1.48 (1.09–2.03)

1.93 (1.33–2.81)

28

1.5%

1.35 (0.87–2.10)

1.55 (0.93–2.58)

Neonatal jaundice

206

3.3%

249

4.6%

1.41 (1.17–1.70)

1.72 (1.39–2.14)

84

4.6%

1.41 (1.09–1.83)

1.58 (1.17–2.13)

Birth injury

16

0.3%

9

0.2%

0.65 (0.29–1.49)

0.85 (0.35–2.06)

4

0.2%

0.85 (0.29–2.56)

0.85 (0.25–2.85)

  1. LBW low birth weight, NRDS neonatal respiratory distress syndrome, TTN transient tachypnea of newborn(TTN)
  2. Model 1: all ORs adjusted for birth place, insurance, age at the second delivery, height, maternal BMI, educational level, gravidity, interpregnancy interval, PIH, GDM, ICP, gestational anaemia, PROM and meconium-staining of the amniotic fluid, AFV, fetal distress, placental abruption, placenta previa, placenta accreta, rupture of uterus, antepartum fever
  3. Model 2: all ORs adjusted for insurance, marital status, age at the second delivery, height, maternal BMI, educational level, gravidity, interpregnancy interval, PIH, GDM, gestational anaemia, PROM and meconium-staining of the amniotic fluid, AFV, fetal distress, placenta previa, placenta accreta, rupture of uterus
  4. aORs further adjusted for stillbirth at the first birth
  5. bORs further adjusted for preterm delivery at the first birth
  6. cORs further adjusted for LBW at the first birth
  7. dORs further adjusted for macrosomia at the first birth