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Table 3 Adverse pregnancy outcomes and the anthropometric parameters in babies in the control and the study group

From: Obstetric outcomes and effects on babies born to women treated for epilepsy during pregnancy in a resource limited setting: a comparative cohort study

 

AED group

N = 75 (%)

Controls

N = 53 (%)

P

Average age of the baby at examination (months) (SD)

 The total study population (N = 75)

5.8 (+/− 6.73)

  

 Cases matched with controls (N = 53)

3.52 (2.79)

3.11 (+/−2.28)

0.30

Average POAa at delivery (weeks) (SD)

38.22 (+/−3.50)

38.52 (+/− 2.06)

 

Term deliveries

70 (92.1)

48 (90.5)

0.66

Preterm deliveries

5 (6.57)

2 (3.77)

0.49

Sex of the baby

 Male

43 (57.33)

29 (54.71)

0.76

 Female

32 (42.66)

24 (45.28)

0.76

Mode of delivery

 NVDb

55 (73.33)

34 (64.15)

0.26

 Forceps delivery

1 (1.33)

1 (1.88)

0.80

 Vacuum delivery

1 (1.33)

3 (5.66)

0.16

 Elective LSCSc

6 (8)

9 (16.19)

0.06

 Emergency LSCSc

10 (13.33)

7 (13.20)

0.23

Intrauterine growth retardation (IUGR)

7 (9.33)

1 (1.88)

0.87

Low birth weight

16 (21.33)

4 (−7.54)

0.03

Examination findings in babies

N = 53

N = 53

 

Congenital abnormalities (n,%)

5 (9.43)

2 (3.77)

0.24

 Atrio-ventricular septal defect

2 (3.77)

0

–

 Renal hypoplasia

1 (1.88)

0

–

 Cryptorchidism

1 (1.88)

0

–

 Microcephaly

1 (1.88)

2 (3.77)

0.35

 Anencephaly

0

0

–

 Neural tube defects

0

0

–

 Cleft palate

0

0

–

Facial measurements (cm)

 Inner-canthal distance

3.02

2.4

0.32

 Outer-canthal distance

9.3

8.37

0.83

 Hair line to chin distance

12.8

12.15

0.24

Facial dysmorphism

 Mid-facial hypoplasia

1 (1.66%)

2 (3.77%)

0.16

 Smooth philtrum

(Astley–Clarren scale 4 &5)

16 (28.07%)

1 (1.88%)

0.0004

 Hypertelorism

1 (1.88%)

1 (1.88%)

0.74

 Telecanthus

1 (1.88%)

0

–

 Epicanthic folds

1 (1.88%)

0

–

 Simian crease

0 (1.88%)

0

–

Anthropometry

 At birth

Weight (Kg)

2.74

2.91

0.263

Length (cm)

51.52

51.53

0.363

OFCd (cm)

32.13

32.85

0.307

 At the postpartum visit

Weight (Kg)

4.12

4.97

0.009

Length (cm)

55.53

58.09

0.016

OFCd (cm)

37.37

39.49

0.002

  1. aPeriod of amenorrhea
  2. bNormal vaginal delivery
  3. clower segment cesarean section
  4. dOccipito-frontal circumference